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CAS No 92118-27-9 , 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea Search by region : China

  • Name: 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea
  • Synonyms: Fotemustinum [Latin];Muphoran;1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea; 92118-27-9; S-10036; S 10036; Fotemustina [Spanish]; CCRIS 6337; Servier-10036;
  • CAS Registry Number:
  • Melting Point: 85 deg C
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.37 g/cm3
  • Refractive index: 1.524
  • Flash Point: °C
  • Molecular Weight: 315.691022
  • InchiKey: YAKWPXVTIGTRJH-UHFFFAOYSA-N
  • InChI: InChI=1S/C9H19ClN3O5P/c1-4-17-19(16,
    18-5-2)8(3)11-9(14)13(12-15)7-6-10/h8H,4-7H2,1-3H3,(H,11,14)
  • Molecular Formula: C9H19ClN3O5P
  • Molecular Structure:CAS No:92118-27-9 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea

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References of 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea
Title: Fotemustine
CAS Registry Number: 92118-27-9
CAS Name: [1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]phosphonic acid diethyl ester
Synonyms: (±)-diethyl [1-[3-(2-chloroethyl)-3-nitrosoureido]ethyl]phosphonate; 1-[N-(2-chloroethyl)-N-nitrosoureido]ethylphosphonic acid diethyl ester
Manufacturers' Codes: S-10036
Trademarks: Muphoran (Servier)
Molecular Formula: C9H19ClN3O5P
Molecular Weight: 315.69
Percent Composition: C 34.24%, H 6.07%, Cl 11.23%, N 13.31%, O 25.34%, P 9.81%
Literature References: Amino acid-linked nitrosourea alkylating agent. Prepn: G. Lavielle, C. Cudennec, FR 2536075; eidem, US 4567169 (1984, 1986 both to ADIR). Clinical evaluation in advanced cancers: D. Khayat et al., Cancer Res. 47, 6782 (1987); in disseminated malignant melanoma: D. Khayat et al., J. Natl. Cancer Inst. 80, 1407 (1988).
Properties: mp 85°.
Melting point: mp 85°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Nitrosoureas.