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CAS No 759-73-9 , 1-ethyl-1-nitrosourea

  • Name: 1-ethyl-1-nitrosourea
  • Synonyms: N-Ethyl-N-nitrosourea;1-ethyl-1-nitrosourea; Ethylnitrosourea; Ethyl nitrosourea; N-Ethylnitrosourea; Nitrosoethylurea; 1-Ethyl-1-nitrosourea; N-NITROSO-N-ETHYLUREA;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 3
  • Melting Point: 103-1040C (dec)
  • Flash Point: 63.8°C
  • Boiling Point: 181.8°C at 760 mmHg
  • Density: 1.35g/cm3
  • Refractive index: 1.532
  • Safety Statements: Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
  • Hazard Symbols: T
  • Flash Point: 63.8°C
  • EINECS: 212-072-2
  • Molecular Weight: 117.10658
  • InchiKey: FUSGACRLAFQQRL-UHFFFAOYSA-N
  • InChI: InChI=1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)
  • Risk Statements: 45-46-61-20/21/22
  • Molecular Formula: C3H7N3O2
  • Molecular Structure:CAS No:759-73-9 1-ethyl-1-nitrosourea

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References of 1-ethyl-1-nitrosourea
Title: N-Ethyl-N-nitrosourea
CAS Registry Number: 759-73-9
Synonyms: N-Nitroso-N-ethylurea; ENU
Molecular Formula: C3H7N3O2
Molecular Weight: 117.11
Percent Composition: C 30.77%, H 6.02%, N 35.88%, O 27.32%
Line Formula: C2H5N(NO)CONH2
Literature References: Potent mouse mutagen. Prepn: E. A. Werner, J. Chem. Soc. 115, 1093 (1919); F. Arndt, H. Scholz, Angew. Chem. 46, 47 (1933). Carcinogenicity studies: M. F. Rajewsky, R. Goth, Mol. Base Malig., Sel. Pap. Int. Symp. 1976, 2. Mutagenicity studies: W. L. Russell et al., Proc. Natl. Acad. Sci. USA 16, 5818 (1979). Toxicity studies: H. Druckrey et al., Nature 210, 1378 (1966).
Properties: Pale buff-yellow, hexagonal plates, mp 103-104°. LD50 i.v. in rats: 240 mg/kg (Druckrey).
Melting point: mp 103-104°
Toxicity data: LD50 i.v. in rats: 240 mg/kg (Druckrey)
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-201.
Use: Exptlly as mutagen; ethylating agent.