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CAS No 90-89-1 , N,N-diethyl-4-methylpiperazine-1-carboxamide

  • Name: N,N-diethyl-4-methylpiperazine-1-carboxamide
  • Synonyms: Carbamazine; Carbilazine; Cypip; Caricide; Hetrazan; Banocide; Bitirazine; Notezine; Caracide;N,N-diethyl-4-methylpiperazine-1-carboxamide;
  • CAS Registry Number:
  • Melting Point: 137 - 140 C
  • Flash Point: 98 C
  • Density: 1.013g/cm3
  • Refractive index: 1.492
  • Safety Statements: Poison by intraperitoneal route. Human systemic effects by ingestion: allergic dermatitis. An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl. An additive permitted in the food and drinking water of animals and/or for the treatment of food-producing animals.
  • Hazard Symbols: UN NO.
  • Flash Point: 98 C
  • EINECS: 216-696-6
  • Molecular Weight: 199.29324
  • InchiKey: RCKMWOKWVGPNJF-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H21N3O/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13/h4-9H2,1-3H3
  • Molecular Formula: C10H21N3O
  • Molecular Structure:CAS No:90-89-1 N,N-diethyl-4-methylpiperazine-1-carboxamide
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90-89-1 Diethylcarbamazine

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90-89-1 Diethylcarbamazine

  • United States CBSCHEM LIMITED null
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  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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90-89-1 DIETHYL CARBAMAZINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
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  • Address: Rm.902 Longyin Plaza,
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    (N)Nanjing 210009,China null,nullChina
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References of N,N-diethyl-4-methylpiperazine-1-carboxamide
Title: Diethylcarbamazine
CAS Registry Number: 90-89-1
CAS Name: N,N-Diethyl-4-methyl-1-piperazinecarboxamide
Synonyms: 1-diethylcarbamoyl-4-methylpiperazine; carbamazine; 1-diethylcarbamyl-4-methylpiperazine
Manufacturers' Codes: 84L; RP-3799
Trademarks: Carbilazine; Caricide (Am. Cyanamid); Cypip (Am. Cyanamid); Ethodryl (BDH); Notézine (Specia); Spatonin
Molecular Formula: C10H21N3O
Molecular Weight: 199.29
Percent Composition: C 60.27%, H 10.62%, N 21.08%, O 8.03%
Literature References: Prepn: Kushner et al., J. Org. Chem. 13, 151 (1948); Kushner, Brancone, US 2467893; US 2467895 (1949 to Am. Cyanamid). Pharmacology and toxicology: Harned et al., Ann. N.Y. Acad. Sci. 50, 141 (1948). GC determn in blood: S. Nene et al., J. Chromatogr. 308, 334 (1984). Mode of action: J.-Y. Cesbron et al., Nature 325, 533 (1987). Review of pharmacology, mechanisms of action and clinical uses: C. D. MacKenzie, M. A. Kron, Trop. Dis. Bull. 82(10), R1-R37 (1985).
Properties: Crystals, mp 47-49°. bp3 108.5-111°.
Melting point: mp 47-49°
Boiling point: bp3 108.5-111°
 
Derivative Type: Hydrochloride
Molecular Formula: C10H21N3O.HCl
Molecular Weight: 235.75
Percent Composition: C 50.95%, H 9.41%, N 17.82%, O 6.79%, Cl 15.04%
Properties: Crystals from acetone, mp 156.5-157°. Very sol in water; sol in chloroform, dioxane.
Melting point: mp 156.5-157°
 
Derivative Type: Citrate
CAS Registry Number: 1642-54-2
Trademarks: Banocide (Wellcome); Dec (Wendt); Dirocide (Solvay); Filaribits (SKB); Filazine; Franocide (Burroughs Wellcome); Hetrazan (Lederle); Loxuran (EGYT); Longicid (Chassot)
Molecular Formula: C10H21N3O.C6H8O7
Molecular Weight: 391.42
Percent Composition: C 49.10%, H 7.47%, N 10.74%, O 32.70%
Properties: Crystals, mp 141-143°. Freely sol in water (>75% at 20°). Sparingly sol in cold alc; freely sol in hot alc. Practically insol in benzene, acetone, ether, chloroform. LD50 orally in rats: 1.38 g/kg (Harned).
Melting point: mp 141-143°
Toxicity data: LD50 orally in rats: 1.38 g/kg (Harned)
 
Derivative Type: Phosphate
Trademarks: Ditrazin
Properties: Crystals, freely sol in water.
 
Therap-Cat: Anthelmintic (Nematodes).
Therap-Cat-Vet: Citrate as an anthelmintic.
Keywords: Anthelmintic (Nematodes).