References of methyl
(1R,15S,17R,18R,19S,20S)-17-(4-ethoxycarbonyloxy-3,
5-dimethoxybenzoyl)oxy-6,18-dimethoxy-1,3,11,12,14,15,16,17,18,19,20,
21-dodecahydroyohimban-19-carboxylate
Title: Syrosingopine
CAS Registry Number: 84-36-6
CAS Name: 18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic acid methyl ester
Synonyms: methyl carbethoxysyringoyl reserpate; carbethoxysyringoyl methyl reserpate; methyl
O-(
O¢-carbethoxysyringoyl)reserpate; syringopine
Manufacturers' Codes: Su-3118
Trademarks: Isotense (Nicholas); Londomin (Taiyo); Raunova (Zambeletti); Seniramin (Hokuriku); Siringina (Toyo Jozo)
Molecular Formula: C35H42N2O11
Molecular Weight: 666.71
Percent Composition: C 63.05%, H 6.35%, N 4.20%, O 26.40%
Literature References: Prepn: Lucas
et al., J. Am. Chem. Soc. 81, 1928 (1959);
US 2813871 (1957 to Ciba).
Properties: Crystals from acetone, mp 175-179°.
Melting point: mp 175-179°
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive; Reserpine Derivatives.