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CAS No 81103-11-9 , Clarithromycin

  • Name: Clarithromycin
  • Synonyms: Klacid; A-56268;Clarithromycin; A-56268; Biaxin; Klacid; TE-03; TE-03;6-O-Methylerythromycin; Biaxin;
  • CAS Registry Number:
  • Transport: MAC
  • Melting Point: 217-220 ºC
  • Density: 1.18 g/cm3
  • Refractive index: -92 ° (C=1, CHCl3)
  • Water Solubility: Insoluble
  • Safety Statements: 26-36
  • Hazard Symbols: Xi: Irritant;Xn: Harmful;
  • HS Code: 29419000
  • Molecular Weight: 747.96
  • InChI: InChI=1/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20?,21+,22+,23-,24?,25?,26-,27?,29?,30+,31-,32?,33-,35?,36?,37-,38-/m1/s1
  • Risk Statements: 22-36/37/38
  • Molecular Formula: C38H69NO13
  • Molecular Structure:CAS No:81103-11-9 Clarithromycin
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81103-11-9 Clarithromycin USP34

  • "Appearance A white or almost white crystalline powder Solubility Practically insoluble in water,freely soluble in methylene chloride,soluble in acetone, slightly soluble in methanol,dehydrated alcohol and in acetonitrile.Slightly soluble in phosphat...
  • China Hangzhou Dingyan Chem Co.,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-571-88025800
  • Fax: 86-571-87156470
  • Address: Xiasha 571, 19TH Street E-COMMERCE 4A 601-602 , Jianggan Area hangzhou,ZhejiangChina

81103-11-9 Clarithromycin

  • Name : Clarithromycin Synonyms: 6-O-Methylerythromycin; A-56268; Biaxin; Klacid; TE-03 Molecular Formula: C38H69NO13 Molecular Weight: 747.96 CAS Registry Number: 81103-11-9 Appearance: white or almost white crystalline powder Functions: broad-spectr...
  • China Daxinganling International Import & Export Co., Ltd. [Manufacturer]
  • Tel: 86-452-6197119
  • Address: 5F, C Liandalijing Bulding,No 259 Xinjiang Road, Jianhua District qiqihar,HeilongjiangChina
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81103-11-9 Clarithromycin

  • Name : Clarithromycin Synonyms: 6-O-Methylerythromycin; A-56268; Biaxin; Klacid; TE-03 Molecular Formula: C38H69NO13 Molecular Weight: 747.96 CAS Registry Number: 81103-11-9 Appearance: white or almost white crystalline powder Functions: broad-spectr...
  • China DaXingAnLing Zhongbei Northland Bio-Chem Industry Co., Ltd [Manufacturer]
  • Tel: 86-452-6197119
  • Address: 5F, C Liandalijing Bulding,No 259 Xinjiang Road, Jianhua District Qiqihar,HeilongjiangChina
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81103-11-9 Clarithromycin

  • Clarithromycin Chemical Name: 6-O-Methylerythromycin Molecular Formula: C38H 69NO13 Molecular Weight: 747.95 CAS Number: 81103-11-9 Appearance: White to off-white crystalline powder Application: Clarithromycin is used to treat certain infections caus...
  • China Wuhan Changland Technology Co.Ltd [Manufacturer]
  • Tel: 86-27-87290719
  • Fax: 86-27-68786490
  • Address: Changland Technology Co.,LTD Wuhan,HubeiChina
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81103-11-9 Clarithromycin

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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81103-11-9 Clarithromycin

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
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81103-11-9 Clarithromycin

  • ClarithromycinClarithromycin, 98%
  • China PMIDA AGROCHEMICAL CO.,LTD [Manufacturer]
  • Tel: +86-023-67030808-8010
  • Fax: +86-023-67030809
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone401121 ChongqingCHINA Chongqing,China
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81103-11-9 Clarithromycin

  • Clarithromycin, 98%
  • China Shanghai Rainbow Chemistry Co., Ltd. [Manufacturer]
  • Tel: +86-21-64968086
  • Fax: +86-21-64968086
  • Address: Room 128, Building B, No. 8 Lane 1305, Huajing Road, Xuhui District, Shanghai, P.R. China 200000 Shanghai CHINA Shanghai,China
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81103-11-9 Clarithromycin

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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81103-11-9 Clarithromycin

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References of Clarithromycin
Title: Clarithromycin
CAS Registry Number: 81103-11-9
CAS Name: 6-O-Methylerythromycin
Manufacturers' Codes: A-56268; TE-031
Trademarks: Biaxin (Abbott); Clarosip (Grñenthal); Clathromycin (Taisho); Cyllind (Abbott); Klacid (Abbott); Klaricid (Abbott); Macladin (Guidotti); Naxy (Sanofi Winthrop); Veclam (Zambon); Zeclar (Abbott)
Molecular Formula: C38H69NO13
Molecular Weight: 747.95
Percent Composition: C 61.02%, H 9.30%, N 1.87%, O 27.81%
Literature References: Semisynthetic macrolide antibiotic; derivative of erythromycin, q.v. Prepn: Y. Watanabe et al., EP 41355; eidem, US 4331803 (1981, 1982 both to Taisho); and in vitro antibacterial activity: S. Morimoto et al., J. Antibiot. 37, 187 (1984). In vitro and in vivo antibacterial activity: P. B. Fernandes et al., Antimicrob. Agents Chemother. 30, 865 (1986). Comparative antibacterial spectrum in vitro: C. Benson et al., Eur. J. Clin. Microbiol. 6, 173 (1987); H. M. Wexler, S. M. Finegold, ibid. 492. HPLC determn in biological fluids: D. Croteau et al., J. Chromatogr. 419, 205 (1987); in plasma: H. Amini, A. Ahmadiani, J. Chromatogr. B 817, 193 (2005). Acute toxicity study: S. Abe et al., Chemotherapy (Tokyo) 36, Suppl. 3, 274 (1988). Symposium on pharmacology and comparative clinical studies: J. Antimicrob. Chemother. 27, Suppl. A, 1-124 (1991). Comprehensive description: I. I. Salem, Anal. Profiles Drug Subs. Excip. 24, 45-85, (1996).
Properties: Colorless needles from chloroform + diisopropyl ether (1:2), mp 217-220° (dec). Also reported as crystals from ethanol, mp 222-225° (Morimoto). uv max (CHCl3): 288 nm (e 27.9). uv max (CHCl3): 240, 288 nm; (methanol): 211, 288 nm. [a]D24 -90.4° (c = 1 in CHCl3). Stable at acidic pH. LD50 in male, female mice, male, female rats (mg/kg): 2740, 2700, 3470, 2700 orally, 1030, 850, 669, 753 i.p., >5000 all s.c. (Abe).
Melting point: mp 217-220° (dec); mp 222-225° (Morimoto)
Optical Rotation: [a]D24 -90.4° (c = 1 in CHCl3)
Absorption maximum: uv max (CHCl3): 288 nm (e 27.9). uv max (CHCl3): 240, 288 nm
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 2740, 2700, 3470, 2700 orally, 1030, 850, 669, 753 i.p., >5000 all s.c. (Abe)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Macrolides.