Home > Name List By a > Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-

CAS No 80471-63-2 , Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-

  • Name: Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-
  • Synonyms: FT-0667915;Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-; AG-H-23535;CTK8F9472; (4|A,5|A,17|A)-4,5-Epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile;
  • CAS Registry Number:
  • Flash Point: 253.2°C
  • Boiling Point: 495°C at 760 mmHg
  • Density: 1.24g/cm3
  • Refractive index: 1.596
  • Safety Statements: Human toxic effects by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 253.2°C
  • Molecular Weight: 357.48644
  • InchiKey: QBEXHJRIQYMCMI-KMMJEOBNSA-N
  • InChI: InChI=1S/C22H31NO3/c1-18-9-7-15-13(14(18)8-10-20(18,3)25)6-11-22-19(15,
    2)12-16(23-5)17(24)21(22,4)26-22/h13-15,24-25H,6-12H2,1-4H3/t13-,14-,
    15-,18-,19+,20-,21+,22-/m0/s1
  • Molecular Formula: C22H31NO3
  • Molecular Structure:CAS No:80471-63-2 Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-

Related products

Search by region :

Select to

80471-63-2 EPOSTANE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

80471-63-2 Epostane

Contact Supplier

80471-63-2 Epostane

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
Contact Supplier

80471-63-2 Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-

  • China SOGA ENTERPRISES ASIA GROUP [Manufacturers]
  • Tel: +86-633-8332928
  • Fax: +86-633-8352255
  • Address: No.1,Huanghai Yilu.Rizhao,Shandong null,ShandongChina
Contact Supplier

Select to

1/1
References of Androst-2-ene-2-carbonitrile,4,5-epoxy-3,17-dihydroxy-4,17-dimethyl-, (4a,5a,17b)-
Title: Epostane
CAS Registry Number: 80471-63-2
CAS Name: (4a,5a,17b)-4,5-Epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile
Synonyms: (2a,4a,5a,17b)-4,5-epoxy-17-hydroxy-4,17-dimethyl-3-oxoandrostane-2-carbonitrile
Manufacturers' Codes: Win-32729
Molecular Formula: C22H31NO3
Molecular Weight: 357.49
Percent Composition: C 73.91%, H 8.74%, N 3.92%, O 13.43%
Literature References: 3b-Hydroxysteroid dehydrogenase inhibitor; derivative of trilostane, q.v. Prepn as ketone tautomer: R. G. Christiansen, DE 2855091; idem, US 4160027 (both 1979 to Sterling). Pharmacology and interceptive activity: J. E. Creange et al., Contraception 24, 289 (1981); R. G. Christiansen et al., J. Med. Chem. 27, 928 (1984). Clinical pharmacology: Z. M. Van der Spuy et al., Clin. Endocrinol. 19, 521 (1983); N. S. Pattison et al., Fertil. Steril. 42, 875 (1984). Clinical evaluation as abortifacient: L. Birgerson et al., Contraception 35, 111 (1987); M. J. Crooij et al., N. Engl. J. Med. 319, 813 (1988). Comparative clinical study with mifepristone, q.v., as abortifacient: L. Birgerson, V. Odlind, Fertil. Steril. 48, 565 (1987). Induction of labor in swine: P. A. Martin et al., J. Anim. Sci. 64, 497 (1987); in sheep: M. Silver, Vet. Rec. 120, 299 (1987). Regulation of ovulation in sheep: R. Webb, J. Reprod. Fertil. 79, 231 (1987). Abortifacient efficacy in dogs: D. M. Keister et al., Theriogenology 30, 497 (1988).
Properties: Crystals, mp 191-194° from DMF/H2O. [a]D25 +67.4° (c = 1 in pyridine).
Melting point: mp 191-194°
Optical Rotation: [a]D25 +67.4° (c = 1 in pyridine)
Therap-Cat: Interceptive.
Therap-Cat-Vet: Interceptive, labor inducer.
Keywords: Abortifacient/Interceptive.