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CAS No 3688-65-1 , Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, 17-oxide, (5a,6a)-

  • Name: Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, 17-oxide, (5a,6a)-
  • Synonyms: Morphinan-6a-ol, 7,8-didehydro-4,5a-epoxy-3-methoxy-17-methyl-, 17-oxide (8CI);Genkodein; Gencodeine; Genocodein; Codeigene;CodeineN-oxide (6CI,7CI); Genocodeine;Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, 17-oxide, (5a,6a)-;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Flash Point: °C
  • EINECS: 222-988-4
  • Molecular Weight: 315.36
  • InChI: InChI=1/C18H21NO4/c1-19(21)8-7-18-11-4-5-13(20)17(18)23-16-14(22-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-,19?/m0/s1
  • Molecular Formula: C18H21 N O4
  • Molecular Structure:CAS No:3688-65-1 Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, 17-oxide, (5a,6a)-
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3688-65-1 CODEINE-N-OXIDE (FREE BASE)

  • Norway Chiron AS [Manufacturer]
  • Tel: +47 73 87 44 90
  • Fax: +47 73 87 44 99
  • Address: Chiron AS
    Stiklestadveien 1
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    Norway null,nullNorway
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3688-65-1 Codeine-N-oxide (free base)

  • Codeine-N-oxide (free base)
  • Norway Chiron AS [Manufacturer]
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  • Address: Stiklestadveien 1N-7041 TrondheimNORWAY Trondheim,nullNorway
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3688-65-1 1567.18-100-ME CODEINE-N-OXIDE (FREE BASE)

  • Germany Campro Scientific GmbH [Manufacturer]
  • Tel: +49.(0)30.629.01.89.0 (Germany)/ +31.(0)318.529.437 (Netherlands)
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  • Address: Campro Scientific GmbH
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3688-65-1 EPL-AA35 CODEINE-N-OXIDE

  • Australia Epichem Pty Ltd [Manufacturer]
  • Tel: +61 8 9360 7696
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  • Address: Epichem Pty Ltd
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    Australia null,nullAustralia
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3688-65-1 CODEINE N-OXIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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References of Morphinan-6-ol,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, 17-oxide, (5a,6a)-
Title: Codeine N-Oxide
CAS Registry Number: 3688-65-1
Synonyms: Genocodeine; genkodein
Trademarks: Codeigene
Molecular Formula: C18H21NO4
Molecular Weight: 315.36
Percent Composition: C 68.55%, H 6.71%, N 4.44%, O 20.29%
Literature References: Prepn from codeine and 30% hydrogen peroxide: Freund, Speyer, Ber. 43, 3313 (1910); Kelentey et al., Arzneim.-Forsch. 7, 594 (1957).
Properties: Platelets from water, mp 231-232°.
Melting point: mp 231-232°
 
Derivative Type: Monohydrate
Properties: Crystals from alc, mp 215°. [a]D18 -97.1° (c = 2.1 in water).
Melting point: mp 215°
Optical Rotation: [a]D18 -97.1° (c = 2.1 in water)
 
Derivative Type: Hydrochloride monohydrate
Molecular Formula: C18H21NO4.HCl.H2O
Molecular Weight: 369.84
Percent Composition: C 58.46%, H 6.54%, N 3.79%, O 21.63%, Cl 9.59%
Properties: Crystals, loses crystal water at 110°, mp 219-220°. [a]D20 -105.8° (c = 2 in water). One gram dissolves in 9.5 ml water.
Melting point: mp 219-220°
Optical Rotation: [a]D20 -105.8° (c = 2 in water)
 
CAUTION: May be habit forming: 21 CFR, 329.1 and is a controlled substance (opium derivative): 21 CFR, 1308.11.
Therap-Cat: Antitussive.
Keywords: Antitussive.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.