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CAS No 78415-72-2 , 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile

  • Name: 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
  • Synonyms: Corotrop; Milrinonum; Milrila;6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile; Milrinona [Spanish]; Milrinonum [Latin]; Milrinona; Corotrope; 78415-72-2;Primacor;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: >3000C
  • Density: 1.28 g/cm3
  • Water Solubility: DMSO: >10 mg/mL
  • Safety Statements: R23/24/25
  • Hazard Symbols: T: Toxic;
  • EINECS: 278-903-6
  • Molecular Weight: 211.21936
  • InchiKey: PZRHRDRVRGEVNW-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,
    (H,15,16)
  • Risk Statements: S36/37/39;S45
  • Molecular Formula: C12H9N3O
  • Molecular Structure:CAS No:78415-72-2 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
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78415-72-2 milrinone

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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78415-72-2 milrinone

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78415-72-2 milrinone

  • China Watson International Ltd. []
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, ,China
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78415-72-2 milrinone

  • IUPAC NAME-2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile MOLECULAR FORMULA-C12H9N3O MOLAR MASS-211.219 g/moL Milrinone, commonly known and marketed as the drug Primacor, is a medication used in patients suffering from heart failure. Milri...
  • India Swapnroop Drugs and Pharmaceuticals [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool aurangabad,maharashtraIndia
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78415-72-2 milrinone

  • China Xilin Chemical Group Co., Ltd []
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, ,China
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78415-72-2 MILRINONE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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78415-72-2 Milrinone

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78415-72-2 Milrinone

  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
  • Tel: +86-(21)-58116473
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  • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
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References of 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
Title: Milrinone
CAS Registry Number: 78415-72-2
CAS Name: 1,6-Dihydro-2-methyl-6-oxo-(3,4¢-bipyridine)-5-carbonitrile
Synonyms: 1,2-dihydro-6-methyl-2-oxo-5-(4-pyridinyl)nicotinonitrile
Manufacturers' Codes: Win-47203
Trademarks: Corotrope (Sanofi-Synthelabo); Milrila (Yamanouchi)
Molecular Formula: C12H9N3O
Molecular Weight: 211.22
Percent Composition: C 68.24%, H 4.29%, N 19.89%, O 7.57%
Literature References: Selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Prepn: G. Y. Lesher et al., BE 886336; G. Y. Lesher, R. E. Philion, US 4313951 (1981, 1982 both to Sterling). Improved process: B. Singh, US 4413127 (1983 to Sterling); idem, Heterocycles 23, 1479 (1985). Pharmacological profile: A. A. Alousi et al., J. Cardiovasc. Pharmacol. 5, 792, 804 (1983). HPLC determn in body fluids: J. Edelson et al., J. Chromatogr. 276, 456 (1983). Clinical studies in congestive heart failure: C. S. Maskin et al., Circulation 67, 1065 (1983); L. S. Sinoway et al., J. Am. Coll. Cardiol. 2, 327 (1983); D. S. Baim et al., N. Engl. J. Med. 309, 748 (1983).
Properties: Crystals from DMF + water or from ethanol, mp >300°.
Melting point: mp >300°
 
Derivative Type: Lactate
CAS Registry Number: 100286-97-3
Trademarks: Primacor (Sanofi-Synthelabo)
Line Formula: C12H9N3O.xC3H6O3
 
Therap-Cat: Cardiotonic.
Keywords: Cardiotonic.