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CAS No 77-86-1 , 2-amino-2-(hydroxymethyl)propane-1,3-diol

  • Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol
  • Synonyms: Tris buffer; Tris(Hydroxymethyl)aminomethane; Trisamine; Tromethane;2-amino-2-(hydroxymethyl)propane-1,3-diol; Trizma;Trometamol; Tris; Tham; 77-86-1;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 167-172 ºC
  • Boiling Point: 219-220 ºC (10 MMHG)
  • Density: 1,353 g/cm3
  • Refractive index: 1.531
  • Water Solubility: 550 G/L (25 ºC)
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • HS Code: 29221980
  • EINECS: 201-064-4
  • Molecular Weight: 121.13504
  • InchiKey: LENZDBCJOHFCAS-UHFFFAOYSA-N
  • InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
  • Risk Statements: S26;S37/39
  • Molecular Formula: C4H11NO3
  • Molecular Structure:CAS No:77-86-1 2-amino-2-(hydroxymethyl)propane-1,3-diol

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77-86-1 Tris(hydroxymethyl)aminomethane

  • product name:Tris(hydroxymethyl)aminomethane; CAS NO.:77-86-1;
  • China Tocopharm Co.,Ltd. [Manufacturer, Other]
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77-86-1 Tris Base

  • Chemreagents is dedicated to bring high quality and cost effective chemical reagents and advanced intermediates to our global customers. Chemreagents has more than 30000 products in stock at our warehouse. In addition to the catalog products, Chemrea...
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77-86-1 Tris Base

  • is an organic compound with the formula (HOCH2)3CNH2. It is extensively used in biochemistry and molecular biology.[1] In biochemistry, Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of...
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77-86-1 Tris(hydroxymethyl)aminomethane

  • Appearance: white crystalline powder MP / BP: 168-171 ℃ Content / Specifications: ≥99.5% Uses: Widely used in the preparation of buffer biochemistry and molecular biology experiments. In addition, Tris, or prepare an intermediate surface active age...
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    • 77-86-1 TRIS

    • "Appearance White crystal Assay 99.50%-101.0% Melting point 168°C-171°C Insolubles 0.03% max ASH 0.05% max Heavy metals 5ppm max Loss on drying 0.2% max PH 10.0-10.8 Color 5# Fe 1ppm max SO42+ 10ppm max Cl 3ppm max Abs (260nm,20%water) 0.1 max"
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    77-86-1 Tris(hydroxymethyl)aminoethane

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    77-86-1 Tris(hydroxymethyl)aminoethane

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    77-86-1 Tris(hydroxymethyl)aminoethane

    • Name:Tris(hydroxymethyl)aminoethane CAS:77-86-1 Synonyms:Tris MF:C4H11NO3 MW:121.14 Purity:≥99% Density:1.353 g/cm3 Melting Point:167-172 °C(lit.) Boiling Point:219-220 °C10 mm Hg(lit.) Flash Point:219-220°C/10mm Appearance:White crystalline or powd...
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    77-86-1 Trometamol

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    77-86-1 Tris(hydroxymethyl)aminoethane

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    References of 2-amino-2-(hydroxymethyl)propane-1,3-diol
    Title: Tromethamine
    CAS Registry Number: 77-86-1
    CAS Name: 2-Amino-2-hydroxymethyl-1,3-propanediol
    Synonyms: trimethylol aminomethane; tris(hydroxymethyl)aminomethane; trisamine; tris buffer; trometamol; tromethane; TRIS
    Trademarks: THAM (Fisher Sci.); Trizma (Sigma-Aldrich)
    Molecular Formula: C4H11NO3
    Molecular Weight: 121.14
    Percent Composition: C 39.66%, H 9.15%, N 11.56%, O 39.62%
    Literature References: May be prepd by reduction or catalytic hydrogenation of the corresp nitro compd. Prepn of similar compds: Hass, Vanderbilt, US 2174242 (1940); Johnson, Degering, J. Org. Chem. 8, 7 (1943); Boileau, Mem. Poudres 35, Annexe 7-76 (1953). Prepn by electrolytic reduction: McMillan, US 2485982 (1949 to Comm. Solvents Corp.). Titrimetric standard: Whitehead, J. Chem. Educ. 36, 297 (1959). Monograph: Ann. N.Y. Acad. Sci. 92, Art. 2, pp 333-812 (June 17, 1961). Crystal structure: R. Rudman et al., Science 200, 531 (1978). GC determn in plasma: H. Hulshoff, H. B. Kostenbauder, J. Chromatogr. 145, 155 (1978). Pharmacokinetics in rabbits: H. Brasch, H. Iven, Arch. Int. Pharmacodyn. 254, 4 (1981). Use as a biological buffer: R. A. Durst, B. R. Staples, Clin. Chem. 18 206 (1972); S. P. Fling, D. S. Gregerson, Anal. Biochem. 155, 83 (1986); T. Higa, D. M. Desiderio, ibid. 173, 463 (1988). Interaction with hydroxyl radicals: M. Hicks, J. M. Gebicki, FEBS Lett. 199, 92 (1986). Review of clinical experience in treatment of acidemia: G. G. Nahas et al., Drugs 55, 191-224 (1998).
    Properties: Crystalline mass, mp 171-172°. bp10 219-220°. Weak, monoacidic base: pKb (25°): 5.91. pKa (20°): 8.3. pKa (37°): 7.82. pH of 0.1 molar aq soln 10.4. Aq solns do not absorb CO2 from the air. Soly at 25° (mg/ml) in water: 550; ethylene glycol: 79.1; methanol: 26; anhydr ethanol: 14.6; 95% ethanol: 22.0; DMF: 14; acetone: 2.0; ethyl acetate: 0.5; olive oil: 0.4; cyclohexane: 0.1; chloroform: 0.05; carbon tetrachloride: <0.05.
    Melting point: mp 171-172°
    Boiling point: bp10 219-220°
    pKa: pKb (25°): 5.91; pKa (20°): 8.3; pKa (37°): 7.82
    Use: In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.
    Therap-Cat: Alkalinizing agent.
    Keywords: Alkalinizing Agent.