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CAS No 72420-38-3 , 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid

  • Name: 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
  • Synonyms: AY 25712;Reductol; D02753;5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid; DSSTox_CID_25685; 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid; AY-25712; 72420-38-3; Acifranum [INN-Latin];
  • CAS Registry Number:
  • Density: 1.343 g/cm3
  • Refractive index: 1.591
  • Molecular Weight: 218.2054
  • InchiKey: DFDGRKNOFOJBAJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,
    1H3,(H,14,15)
  • Molecular Formula: C12H10O4
  • Molecular Structure:CAS No:72420-38-3 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
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72420-38-3 Acifran

  • Acifran, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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72420-38-3 Acifran

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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72420-38-3 Acifran

  • Acifran, > 99.4%
  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland ,Switzerland
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72420-38-3 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid

  • 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acidAcifran, >99%
  • United Kingdom Tocris Bioscience [Manufacturer]
  • Tel: + 44 (0)117 916 3333
  • Fax: + 44 (0)117 916 3344
  • Address: Tocris Bioscience Tocris House Hung Road BS11 9XJ BristolUNITED KINGDOM BS11 9XJ Bristol,United Kingdom
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72420-38-3 Acifran

  • Switzerland Biotrend Chemicals AG [Importer/Exporter]
  • Tel: +41-(44)-805 76 76
  • Fax: +41-(44)-805 76 77
  • Address: Unterdorfstr. 21b, Wangen/Zuerich CH-8602, Wangen/Zürich,Switzerland
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72420-38-3 ACIFRAN

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany ,Germany
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72420-38-3 Acifran

  • Acifran 72420-38-3 Acipimox 51037-30-0 Acteoside 61276-17-3 Aclarubicin 57576-44-0 Acyclovir 59277-89-3 Acitretin 55079-83-9 Adefovir 106941-25-7 Adrenaline 51-43-4
  • China Wuhan Sunrise Technology development company limited [Manufacturers]
  • Tel: +86-27-83314682
  • Fax: 86 27 83314682
  • Address: Floor 5, Wunan Road No.15, Haixia Investment Zone, Wujiashan Wuhan, China Wuhan,HubeiChina
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72420-38-3 2-Furancarboxylic acid,4,5-dihydro-5-methyl-4-oxo-5-phenyl-

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72420-38-3 Acifran

  • Acifran
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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72420-38-3 ACIFRAN; 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
Title: Acifran
CAS Registry Number: 72420-38-3
CAS Name: 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
Synonyms: 2-methyl-2-phenyl-3(2H)-furanone-5-carboxylic acid
Manufacturers' Codes: AY-25712
Trademarks: Reductol (Wyeth-Ayerst)
Molecular Formula: C12H10O4
Molecular Weight: 218.21
Percent Composition: C 66.05%, H 4.62%, O 29.33%
Literature References: Prepd (not claimed): I. L. Jirkovsky et al., US 4169202; prepn and resolution of enantiomers: eidem, US 4244958 (1979, 1981 both to American Home); I. L. Jirkovsky, M. N. Cayen, J. Med. Chem. 25, 1154 (1982). Metabolism and pharmacokinetics in dogs and rats: M. N. Cayen et al., Xenobiotica 16, 251 (1986). LC determn in serum: R. Gonzalez, D. Thibeault, Clin. Biochem. 16, 244 (1983). Clinical evaluation in hyperlipoproteinemia: D. B. Hunninghake et al., Clin. Pharmacol. Ther. 38, 313 (1985); J. C. LaRosa et al., Artery 14, 338 (1987).
Properties: Crystals, mp 176°. uv max (methanol): 281 nm (e 7960). LD50 orally in rats: 3 g/kg (Jirkovsky, 1982).
Melting point: mp 176°
Absorption maximum: uv max (methanol): 281 nm (e 7960)
Toxicity data: LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)
 
Derivative Type: (-)-Form
CAS Registry Number: 77103-92-5
Properties: mp 87-89°. [a]D25 -144.7° (c = 2 in methanol).
Melting point: mp 87-89°
Optical Rotation: [a]D25 -144.7° (c = 2 in methanol)
 
Derivative Type: (+)-Form
CAS Registry Number: 77103-91-4
Properties: mp 87-89°. [a]D25 +146.4° (c = 2 in methanol).
Melting point: mp 87-89°
Optical Rotation: [a]D25 +146.4° (c = 2 in methanol)
 
Therap-Cat: Antilipemic.
Keywords: Antilipemic.