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CAS No 72420-38-3 , 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid Search by region : Germany

  • Name: 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
  • Synonyms: AY 25712;Reductol; D02753;5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid; DSSTox_CID_25685; 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid; AY-25712; 72420-38-3; Acifranum [INN-Latin];
  • CAS Registry Number:
  • Density: 1.343 g/cm3
  • Refractive index: 1.591
  • Molecular Weight: 218.2054
  • InchiKey: DFDGRKNOFOJBAJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,
    1H3,(H,14,15)
  • Molecular Formula: C12H10O4
  • Molecular Structure:CAS No:72420-38-3 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid

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72420-38-3 ACIFRAN

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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72420-38-3 Acifran

  • Acifran
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

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References of 5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
Title: Acifran
CAS Registry Number: 72420-38-3
CAS Name: 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
Synonyms: 2-methyl-2-phenyl-3(2H)-furanone-5-carboxylic acid
Manufacturers' Codes: AY-25712
Trademarks: Reductol (Wyeth-Ayerst)
Molecular Formula: C12H10O4
Molecular Weight: 218.21
Percent Composition: C 66.05%, H 4.62%, O 29.33%
Literature References: Prepd (not claimed): I. L. Jirkovsky et al., US 4169202; prepn and resolution of enantiomers: eidem, US 4244958 (1979, 1981 both to American Home); I. L. Jirkovsky, M. N. Cayen, J. Med. Chem. 25, 1154 (1982). Metabolism and pharmacokinetics in dogs and rats: M. N. Cayen et al., Xenobiotica 16, 251 (1986). LC determn in serum: R. Gonzalez, D. Thibeault, Clin. Biochem. 16, 244 (1983). Clinical evaluation in hyperlipoproteinemia: D. B. Hunninghake et al., Clin. Pharmacol. Ther. 38, 313 (1985); J. C. LaRosa et al., Artery 14, 338 (1987).
Properties: Crystals, mp 176°. uv max (methanol): 281 nm (e 7960). LD50 orally in rats: 3 g/kg (Jirkovsky, 1982).
Melting point: mp 176°
Absorption maximum: uv max (methanol): 281 nm (e 7960)
Toxicity data: LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)
 
Derivative Type: (-)-Form
CAS Registry Number: 77103-92-5
Properties: mp 87-89°. [a]D25 -144.7° (c = 2 in methanol).
Melting point: mp 87-89°
Optical Rotation: [a]D25 -144.7° (c = 2 in methanol)
 
Derivative Type: (+)-Form
CAS Registry Number: 77103-91-4
Properties: mp 87-89°. [a]D25 +146.4° (c = 2 in methanol).
Melting point: mp 87-89°
Optical Rotation: [a]D25 +146.4° (c = 2 in methanol)
 
Therap-Cat: Antilipemic.
Keywords: Antilipemic.