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CAS No 71-73-8 , 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)

  • Name: 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)
  • Synonyms: Barbituricacid, 5-ethyl-5-(1-methylbutyl)-2-thio-, sodium deriv. (7CI); Trapanal; Thiothalsodium; Thiopentone sodium; Sodium 5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate;Penthiobarbital sodium; Trapanal sodium; RS-Thiopental sodium; Leopental; Thiopentobarbitone sodium; Soluble thiopentone; Thionembutal sodium; Barbituric acid,5-ethyl-5-(1-methylbutyl)-2-thio-, sodium salt (8CI);Sodium penthiobarbital; Sodium pentothiobarbital; Sodium 5-ethyl-5-(a-methylbutyl)-2-thiobarbiturate;4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, monosodium salt (9CI); Sodium pentothal; Nesdonal; Intraval sodium;5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid monosodium; Sodium thiopentone; Nesdonal sodium;Ravonal; Pentothal sodium; Tiopental sodium; Sodium thiopentobarbital;4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1); Hypnostan; Pentothal; Thiopental sodium;Thiomebumal sodium; Thionembutal;Intra-Vital Sodium; Sodiumthiopental; Farmotal;Thiopental sodium salt;
  • CAS Registry Number:
  • Safety Statements: Poison by ingestion, intraperitoneal, rectal, subcutaneous, and intravenous routes. Human systemic effects by intraarterial route: acute arterial occlusion; by rectal route: respiratory depression, body temperature decrease, general anesthetic. An experimental teratogen. Experimental reproductive effects. An intravenous anesthetic. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also BARBITURATES.
  • Hazard Symbols: T: Toxic;
  • EINECS: 200-763-1
  • Molecular Weight: 265.36
  • InChI: InChI=1/C11H18N2O2S.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1
  • Risk Statements: 25
  • Molecular Formula: C11H18 N2 O2 S . Na
  • Molecular Structure:CAS No:71-73-8 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)

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71-73-8 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)

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71-73-8 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)

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1/1
References of 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)
Title: Thiopental Sodium
CAS Registry Number: 71-73-8
CAS Name: 5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione monosodium salt
Synonyms: 5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid sodium salt; thiomebumal sodium; penthiobarbital sodium; thiopentone sodium; thionembutal
Trademarks: Intraval Sodium (RPR); Nesdonal Sodium (RPR); Pentothal Sodium (Abbott); Trapanal (Byk Gulden)
Molecular Formula: C11H17N2NaO2S
Molecular Weight: 264.32
Percent Composition: C 49.98%, H 6.48%, N 10.60%, Na 8.70%, O 12.11%, S 12.13%
Literature References: Prepn: US 2153729 (1939); US 2876225 (1959). Prepn of nonhygroscopic crystals: Hartop, US 3109001 (1963 to Abbott). Acute toxicity: Christensen, Lee, Toxicol. Appl. Pharmacol. 26, 495 (1973). Comprehensive description: M. J. McLeish, Anal. Profiles Drug Subs. Excip. 21, 535-572 (1992).
Properties: Yellowish-white, hygroscopic powder. Alliaceous, garlic-like odor. Sol in water, alcohol. Insol in ether, benzene, petr ether. Aq solns are alkaline to litmus. Solns dec on standing; on boiling precipitation occurs. LD50 in mice (mg/kg): 149 i.p.; 78 i.v. (Christensen, Lee).
Toxicity data: LD50 in mice (mg/kg): 149 i.p.; 78 i.v. (Christensen, Lee)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Anesthetic (intravenous).
Therap-Cat-Vet: Short-acting anesthetic.
Keywords: Anesthetic (Intravenous).