CAS No 71-73-8 , 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1) Search by region : China

Name: 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)
Synonyms: Barbituricacid, 5-ethyl-5-(1-methylbutyl)-2-thio-, sodium deriv. (7CI); Trapanal; Thiothalsodium; Thiopentone sodium; Sodium 5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate;Penthiobarbital sodium; Trapanal sodium; RS-Thiopental sodium; Leopental; Thiopentobarbitone sodium; Soluble thiopentone; Thionembutal sodium; Barbituric acid,5-ethyl-5-(1-methylbutyl)-2-thio-, sodium salt (8CI);Sodium penthiobarbital; Sodium pentothiobarbital; Sodium 5-ethyl-5-(a-methylbutyl)-2-thiobarbiturate;4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, monosodium salt (9CI); Sodium pentothal; Nesdonal; Intraval sodium;5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid monosodium; Sodium thiopentone; Nesdonal sodium;Ravonal; Pentothal sodium; Tiopental sodium; Sodium thiopentobarbital;4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1); Hypnostan; Pentothal; Thiopental sodium;Thiomebumal sodium; Thionembutal;Intra-Vital Sodium; Sodiumthiopental; Farmotal;Thiopental sodium salt;
CAS Registry Number:71-73-8
Safety Statements: Poison by ingestion, intraperitoneal, rectal, subcutaneous, and intravenous routes. Human systemic effects by intraarterial route: acute arterial occlusion; by rectal route: respiratory depression, body temperature decrease, general anesthetic. An experimental teratogen. Experimental reproductive effects. An intravenous anesthetic. When heated to decomposition it emits toxic fumes of NO_x and Na₂O. See also BARBITURATES.
Hazard Symbols: T: Toxic;
EINECS: 200-763-1
Molecular Weight: 265.36
InChI: InChI=1/C11H18N2O2S.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1
Risk Statements: 25
Molecular Formula: C11H18 N2 O2 S . Na
Molecular Structure:

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           71-73-8 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)
           
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References of 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)

Title: Thiopental Sodium
CAS Registry Number: 71-73-8
CAS Name: 5-Ethyldihydro-5-(1-methylbutyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione monosodium salt
Synonyms: 5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid sodium salt; thiomebumal sodium; penthiobarbital sodium; thiopentone sodium; thionembutal
Trademarks: Intraval Sodium (RPR); Nesdonal Sodium (RPR); Pentothal Sodium (Abbott); Trapanal (Byk Gulden)
Molecular Formula: C11H17N2NaO2S
Molecular Weight: 264.32
Percent Composition: C 49.98%, H 6.48%, N 10.60%, Na 8.70%, O 12.11%, S 12.13%
Literature References: Prepn: US 2153729 (1939); US 2876225 (1959). Prepn of nonhygroscopic crystals: Hartop, US 3109001 (1963 to Abbott). Acute toxicity: Christensen, Lee, Toxicol. Appl. Pharmacol. 26, 495 (1973). Comprehensive description: M. J. McLeish, Anal. Profiles Drug Subs. Excip. 21, 535-572 (1992).
Properties: Yellowish-white, hygroscopic powder. Alliaceous, garlic-like odor. Sol in water, alcohol. Insol in ether, benzene, petr ether. Aq solns are alkaline to litmus. Solns dec on standing; on boiling precipitation occurs. LD50 in mice (mg/kg): 149 i.p.; 78 i.v. (Christensen, Lee).
Toxicity data: LD50 in mice (mg/kg): 149 i.p.; 78 i.v. (Christensen, Lee)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.13.
Therap-Cat: Anesthetic (intravenous).
Therap-Cat-Vet: Short-acting anesthetic.
Keywords: Anesthetic (Intravenous).