Home > Name List By n > N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]- hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamid...

CAS No 70-51-9 , N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-
hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide

  • Name: N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-
    hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide
  • Synonyms: Deferoxamine B; Deferoxaminum;N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-
    hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide; Desferin; Deferrioxamine; Desferrioxamine B; DESFERRIOXAMINE; Deferoxamin;Deferrioxamine B;
  • CAS Registry Number:
  • Density: 1.212g/cm3
  • Refractive index: 1.537
  • Safety Statements: Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal and subcutaneous routes. Human systemic effects: changes in hearing acuity, eye hemorrhage, optic nerve neuropathy, thrombocytopenia, visual field changes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • EINECS: 200-738-5
  • Molecular Weight: 560.68402
  • InchiKey: UBQYURCVBFRUQT-UHFFFAOYSA-N
  • InChI: InChI=1S/C25H48N6O8/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31
    (39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26/h37-39H,2-20,
    26H2,1H3,(H,27,33)(H,28,34)
  • Molecular Formula: C25H48N6O8
  • Molecular Structure:CAS No:70-51-9 N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-<br />hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide

Related products

Search by region :

Select to

70-51-9 Deferoxamine

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
Contact Supplier

70-51-9 deferoxamine

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
Contact Supplier

70-51-9 Deferoxamine

  • China TaiZhou HiKong Chemical Co., Ltd. null
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, null,nullChina
Contact Supplier

70-51-9 DEFEROXAMINE

Contact Supplier

70-51-9 deferoxamine

Contact Supplier

70-51-9 Deferoxamine

  • China Zibo Dingjin Chemical Co.,Ltd. [Manufacturers]
  • Tel: +86-(533)-533-6955, 533-5955
  • Fax: +86-(533)-533-4766
  • Address: Shuangfeng Technological & Industrial Zone(Huayang Pharm), Zibo, Shandong 255190, zibo,shandongChina
Contact Supplier

70-51-9 DEFEROXAMINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-
hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide
Title: Deferoxamine
CAS Registry Number: 70-51-9
CAS Name: N￠-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxybutanediamide
Synonyms: N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic acid; 1-amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(N-acetylhydroxylamino)-6,11,17,22-tetraazaheptaeicosane; desferrioxamine B
Molecular Formula: C25H48N6O8
Molecular Weight: 560.68
Percent Composition: C 53.55%, H 8.63%, N 14.99%, O 22.83%
Literature References: Natural product forming iron complexes, isolated from Streptomyces pilosus Ettlinger et al. Prepn from ferrioxamine B and structure: H. Bickel et al., Helv. Chim. Acta 43, 2129 (1960). Syntheses: V. Prelog, A. Walser, ibid. 45, 631 (1962); BE 609053; E. Gaeumann et al., US 3471476 (l962, 1969 both to Ciba). Derivatives: H. Bickel et al., Helv. Chim. Acta 46, 1385 (1963). Clinical efficacy in thallasemia major (Cooley's anemia): B. Modell et al., Br. Med. J. 284, 1081 (1982). Treatment of hemodialysis-induced aluminum accumulation in brain: P. Ackril et al, Lancet 2, 692 (1980); in bone: H. H. Malluche et al., N. Engl. J. Med. 311, 140 (1984). Neurotoxicity study: N. F. Olivieri et al., ibid. 314, 869 (1986). Review of clinical experience: R. Propper, D. Nathan, Annu. Rev. Med. 33, 509-519 (1982).
 
Derivative Type: Monohydrate
Properties: Crystals from dil alcohol, mp 138-140°. Sol in water at 20°: 1.2%.
Melting point: mp 138-140°
 
Derivative Type: Hydrochloride
CAS Registry Number: 1950-39-6
Manufacturers' Codes: Ba-29837
Molecular Formula: C25H48N6O8.HCl
Molecular Weight: 597.14
Percent Composition: C 50.28%, H 8.27%, N 14.07%, O 21.43%, Cl 5.94%
Properties: Crystals from slightly acidic methanol, mp 172-175°.
Melting point: mp 172-175°
 
Derivative Type: Methanesulfonate
CAS Registry Number: 138-14-7
Synonyms: Desferrioxamine mesylate; DFOM
Trademarks: Desferal (Novartis)
Molecular Formula: C25H48N6O8.CH3SO3H
Molecular Weight: 656.79
Percent Composition: C 47.55%, H 7.98%, N 12.80%, O 26.80%, S 4.88%
Properties: Crystals from dil alcohol, mp 148-149°. Sol in water at 20°: >20%.
Melting point: mp 148-149°
 
Derivative Type: N-Acetyl derivative
Synonyms: N-Acetyldeferoxamine; N-acetyldesferrioxamine B
Molecular Formula: C27H50N6O9
Molecular Weight: 602.72
Percent Composition: C 53.80%, H 8.36%, N 13.94%, O 23.89%
Properties: Crystals from n-propanol, mp 180-182°.
Melting point: mp 180-182°
 
Derivative Type: Iron complex
Synonyms: Ferrioxamine B
Molecular Formula: C25H45FeN6O8
Molecular Weight: 613.51
Percent Composition: C 48.94%, H 7.39%, Fe 9.10%, N 13.70%, O 20.86%
Literature References: A natural microbial growth factor. Isoln: H. Bickel et al., Helv. Chim. Acta 43, 2118 (1960); E. Gaeumann et al., US 3118823; US 3153621 (both 1964 to Ciba).
 
NOTE: Reviews on iron-containing metabolites with growth stimulating properties, sideramines, or with antibiotic properties, sideromycins, ferrimycins: H. Bickel et al., Experientia 16, 129-133 (1960); V. Prelog, Pure Appl. Chem. 6, 327-338 (1963); F. Knüsel, J. Nüesch, Nature 206, 674-676 (l965); T. F. Emery, Adv. Enzymol. Relat. Areas Mol. Biol. 35, 135-185 (1971); Knüsel, Zimmermann, in Antibiotics vol. 3, J. W. Corcoran, F. E. Hahn, Eds. (Springer-Verlag, New York, 1975) pp 653-667.
Therap-Cat: Parenteral chelating agent (iron and aluminum). Methanesulfonate as antidote to iron poisoning.
Keywords: Antidote (Heavy Metal Poisoning); Chelating Agent.