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CAS No 63516-07-4 , Flutropium bromide

  • Name: Flutropium bromide
  • Synonyms: Flutropium bromide;[8-(2-Fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-hydroxy-2,2-diphenylacetate bromide;
  • CAS Registry Number:
  • Safety Statements: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx, Br, and Cl.
  • Molecular Weight: 478.39
  • InChI: InChI=1/C24H29FNO3.BrH/c1-26(15-14-25)20-12-13-21(26)17-22(16-20)29-23(27)24(28,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,20-22,28H,12-17H2,1H3;1H/q+1;/p-1/t20-,21-,22-,26?;/m1./s1
  • Molecular Formula: C24H29BrFNO3
  • Molecular Structure:CAS No:63516-07-4 Flutropium bromide
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63516-07-4 FLUTROPIUM BROMIDE 98.5%

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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63516-07-4 flutropium bromide

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
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  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi ,ShanXiChina
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63516-07-4 Flutropium Bromide

  • Flutropium Bromide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
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  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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63516-07-4 Flutropium Bromide

  • Flutropium Bromide, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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63516-07-4 Flutropium Bromide

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63516-07-4 Flutropium bromide

  • Flutropium bromide 63516-07-4 B130670
  • China bepharm ltd. []
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China ,China
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63516-07-4 flutropium bromide

  • China Hangzhou APIChem Technology Co., Ltd. [Manufacturers]
  • Tel: +86-571-56059907
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  • Address: Hangzhou E&T Development Zone, Hangzhou, Zhejiang, 310018, China Hangzhou,ZhejiangChina
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63516-07-4 flutropium bromide

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63516-07-4 flutropium bromide

  • China TPNChina [Importer/Exporter]
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  • Address: No.2577,Dongfang Road,Weifang,China Shanghai,ShanghaiChina
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63516-07-4 FLUTROPIUM BROMIDE

  • China Beijing Mediking Biopharm Co., Ltd [Manufacturer]
  • Tel: +86-10-81769620/ +86-10-81769521
  • Fax: +86-10-81769652
  • Address: Hongxianghong Incubator, Beiqijia Town,
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    Beijing China ,China
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References of Flutropium bromide
Title: Flutropium Bromide
CAS Registry Number: 63516-07-4
CAS Name: (endo,syn)-8-(2-Fluoroethyl)-3-[(hydroxydiphenylacetyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Synonyms: (8r)-3a-benziloyloxy-8-(2-fluoroethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide; (8r)-8-(2-fluoroethyl)-3a-hydroxy-1aH,5aH-tropanium bromide benzilate; N-b-fluoroethylnortropine benzilate methobromide; benzilic acid N-b-fluoroethylnortropine ester methobromide
Manufacturers' Codes: Ba-598Br
Trademarks: Flubron (SS Pharm.)
Molecular Formula: C24H29BrFNO3
Molecular Weight: 478.39
Percent Composition: C 60.26%, H 6.11%, Br 16.70%, F 3.97%, N 2.93%, O 10.03%
Literature References: Anticholinergic agent. Prepn: R. Banholzer et al., DE 2540633; eidem, US 4042700 (both 1977 to Boehringer, Ing.). Synthesis: R. Banholzer et al., Arzneim.-Forsch. 36, 1161 (1986). Molecular and crystal structure: G. Kiel, ibid. 1166. Pharmacology in animals: S. Yanaura et al., Jpn. J. Pharmacol. 33, 971 (1983); R. Bauer, A. Fügner, Arzneim.-Forsch. 36, 1348 (1986). Pharmacodynamics: K. Yoshimura et al., Iyakuhin Kenkyu 18, 240 (1987), C.A. 107, 17197v (1987).
Properties: White crystals from acetonitrile, mp 192-193° (dec); from ethanol-acetone, mp 198-199° (dec). LD50 in male, female mice, male, female rats (mg/kg): 12.5, 11.0, 16.4, 18.4 i.v.; 760, 810, 830, 740 orally (Bauer, Fügner).
Melting point: mp 192-193° (dec); mp 198-199° (dec)
Toxicity data: LD50 in male, female mice, male, female rats (mg/kg): 12.5, 11.0, 16.4, 18.4 i.v.; 760, 810, 830, 740 orally (Bauer, Fügner)
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Quaternary Ammonium Compounds; Antimuscarinic.