Home > Name List By other > [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3, 4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

CAS No 63-39-8 , [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,
4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen
phosphate

  • Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,
    4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen
    phosphate
  • Synonyms: CHEBI:15713; 63-39-8; Uridine 5'-(tetrahydrogen triphosphate); Uteplex;uridine 5'-triphosphate; Uridine 5'-triphosphoric acid; 5'-UTP;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,
    4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen
    phosphate; UTP;
  • CAS Registry Number:
  • Flash Point: 113 °C
  • Density: 2.106 g/cm3
  • Safety Statements: 22-26-36
  • Hazard Symbols: Xn
  • Flash Point: 113 °C
  • EINECS: 200-558-7
  • Molecular Weight: 484.141086
  • InchiKey: PGAVKCOVUIYSFO-XVFCMESISA-N
  • InChI: InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28
    (19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,
    22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
  • Risk Statements: 20/21/22-68/20/21/22
  • Molecular Formula: C9H15N2O15P3
  • Molecular Structure:CAS No:63-39-8 [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,<br />4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen<br />phosphate
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63-39-8 URIDINE-5''-TRIPHOSPHORIC ACID = UTP

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

  • Hong kong Achemo Sientific cooperation [Manufacturers]
  • Tel: 00852-39711547
  • Fax: 00852-39711547
  • Address: 38 Plaza,38 Shantung street,MongKoK,kowloon,Hongkong Kowloon,KowloonHong kong
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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

  • Japan Nacalai Tesque, Inc. [Manufacturers]
  • Tel: 81 75 251 1723 81-75-251-1730
  • Fax: 81-75-251-1763
  • Address: Nijo Karasuma, Nakagyo-ku Kyoto 604-0855 Japan Nakagyo-ku,KyotoJapan
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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

  • Germany Pharma Waldhof GmbH [Manufacturer]
  • Tel: +49 (0)211 - 52 60 23/ +49 (0)211 - 52 60 20
  • Fax: +49 (0)211 - 52 60 222
  • Address: Pharma Waldhof GmbH
    Hansaallee 159 D-40549 D?sseldorf
    Germany null,nullGermany
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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

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63-39-8 Uridine 5'-triphosphate

  • Germany Roche Applied Science [Manufacturers]
  • Tel: +49-(621)-759-8568
  • Fax: +49-(621)-759-4083
  • Address: Sandhofer Str. 116, Mannheim, Baden-W?rttemberg D‑68305, Indianapolis,INGermany
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63-39-8 Uridine5'-(tetrahydrogen triphosphate)

  • Canada FERMENTAS Inc. [Importer/Exporter]
  • Tel: +1 800 340 9026
  • Fax: +1 800 472 8322
  • Address: 830 Harrington Court,Burlington Ontario L7N 3N4 Burlington,OntarioCanada
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References of [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,
4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen
phosphate
Title: Uridine 5¢-Triphosphate
CAS Registry Number: 63-39-8
CAS Name: Uridine 5¢-(tetrahydrogen triphosphate)
Synonyms: UTP
Molecular Formula: C9H15N2O15P3
Molecular Weight: 484.14
Percent Composition: C 22.33%, H 3.12%, N 5.79%, O 49.57%, P 19.19%
Literature References: Pyrimidine analog of ATP. Activates chloride channels in epithelial cells; increases ciliary beat frequency and induces degranulation of goblet cells in airway epithelia. Also effects inflammatory cell function and vascular reactivity. Isoln from rabbit muscle: Lipton et al., J. Am. Chem. Soc. 75, 5450 (1953). Synthesis: Kenner et al., J. Chem. Soc. 1954, 2288; Hall, Khorana, J. Am. Chem. Soc. 76, 5056 (1954). Review of bioactivity mediated by nucleotide receptors: S. E. O'Connor, Life Sci. 50, 1657-1664 (1992). Clinical effect on chloride secretion in cystic fibrosis: M. R. Knowles et al., Am. J. Respir. Crit. Care Med. 151, S65 (1995); on mucociliary clearance in combination with amiloride, q.v.: W. D. Bennett et al., ibid. 153, 1796 (1996).
 
Derivative Type: Trisodium salt dihydrate
Trademarks: Uteplex (Am. Home)
Molecular Formula: C9H12N2Na3O15P3.2H2O
Molecular Weight: 586.12
Percent Composition: C 18.44%, H 2.75%, N 4.78%, Na 11.77%, O 46.41%, P 15.85%
Properties: White powder, sol in water, very sparingly sol in alcohol. pKa1 6.6; pKa2 9.5. uv max (pH 7): 262 nm (aM 10,000); (pH 11): 261 nm (aM 8100).
pKa: pKa1 6.6; pKa2 9.5
Absorption maximum: uv max (pH 7): 262 nm (aM 10,000)
 
Therap-Cat: In treatment of cystic fibrosis.