Home > Name List By other > [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7, 11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate

CAS No 63-12-7 , [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,
11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate

  • Name: [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,
    11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate
  • Synonyms: Quantril; Benzchinamidum; Benzoquinamide; Quantryl; Emeticon;[3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,
    11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate; Benzochinamide; Emete-con; Promecon; Benzchinamide;
  • CAS Registry Number:
  • Melting Point: 130-131.5 DEG C
  • Flash Point: 274.9°C
  • Boiling Point: 531°C at 760 mmHg
  • Density: 1.19g/cm3
  • Refractive index: 1.56
  • Flash Point: 274.9°C
  • Molecular Weight: 404.49988
  • InchiKey: JSZILQVIPPROJI-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H32N2O5/c1-6-23(7-2)22(26)17-13-24-9-8-15-10-20(27-4)21(28-
    5)11-16(15)18(24)12-19(17)29-14(3)25/h10-11,17-19H,6-9,12-13H2,1-5H3
  • Molecular Formula: C22H32N2O5
  • Molecular Structure:CAS No:63-12-7 [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,<br />11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate

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References of [3-(diethylcarbamoyl)-9,10-dimethoxy-2,3,4,6,7,
11b-hexahydro-1H-benzo[a]quinolizin-2-yl] acetate
Title: Benzquinamide
CAS Registry Number: 63-12-7
CAS Name: 2-(Acetyloxy)-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizine-3-carboxamide
Synonyms: N,N-diethyl-1,3,4,6,7,11b-hexahydro-2-hydroxy-9,10-dimethoxy-2H-benzo[a]quinolizine-3-carboxamide acetate; 2-acetoxy-3-(N,N-diethylcarboxamido)-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzopyridocoline; 2-hydroxy-3-diethylcarbamyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzoquinolizine acetate; BZQ
Manufacturers' Codes: NSC-64375; P-2647
Trademarks: Emete-Con (Roerig); Promecon (Searle); Quantril (Roerig)
Molecular Formula: C22H32N2O5
Molecular Weight: 404.50
Percent Composition: C 65.32%, H 7.97%, N 6.93%, O 19.78%
Literature References: Prepn: Trettner, US 3053845 (1962 to Pfizer). Pharmacology: Scriabine et al., J. Am. Med. Assoc. 184, 276 (1963); Kadzielawa, Gumulka, Arch. Int. Pharmacodyn. Ther. 163, 139 (1966). Metabolic studies: Koe, Pinson, J. Med. Chem. 7, 635 (1964); Wiseman et al., Biochem. Pharmacol. 13, 1421 (1964). Toxicity: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: Crystals from diisopropyl ether, mp 130-131.5°. LD50 orally in rats: 990 mg/kg; i.p. in mice: 376 mg/kg (Goldenthal).
Melting point: mp 130-131.5°
Toxicity data: LD50 orally in rats: 990 mg/kg; i.p. in mice: 376 mg/kg (Goldenthal)
Therap-Cat: Antipsychotic, antiemetic.
Keywords: Antiemetic; Antipsychotic; Other Tricyclics.