Home > Name List By 6 > 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H- benzimidazol-2-one India

CAS No 57808-66-9 , 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-
benzimidazol-2-one Search by region : India

  • Name: 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-
    benzimidazol-2-one
  • Synonyms: Domperidona; Lopac-D-122; Domperidonum [INN-Latin]; Nauzelin;6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-
    benzimidazol-2-one; NSC299589; Domperidonum;Motilium; 57808-66-9; Domperidon;
  • CAS Registry Number:
  • Melting Point: 242.5 ºC
  • Density: 1.341 g/cm3
  • Water Solubility: DMSO: >10 mg/mL
  • Safety Statements: R62;R63
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 260-968-7
  • Molecular Weight: 425.91126
  • InchiKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26
    (13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,
    8-13H2,(H,24,29)(H,25,30)
  • Risk Statements: S26;S36
  • Molecular Formula: C22H24ClN5O2
  • Molecular Structure:CAS No:57808-66-9 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-<br />benzimidazol-2-one

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57808-66-9 DOMPERIDONE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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57808-66-9 Domperidone

  • India Triveni Chemicals null
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, null,nullIndia
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57808-66-9 Domperidone

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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57808-66-9 DOMPERIDONE

  • DOMPERIDONE5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1 H- benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihy dro-2 H- benzimidazol-2-one, BP/EP EDMF
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
  • Fax: +91 79 30071176, 26574630
  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
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57808-66-9 Domperidone

  • India Exim-Pharm International null
  • Tel: +91-(22)-26191948
  • Fax: +91-(22)-26191948
  • Address: 1, Ashish Mahal, 2nd Floor, Ist Road, Golibar Santacruz (E), Mumbai, Maharashtra 400 055, null,nullIndia
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57808-66-9 Domperidone

  • India Steamline Industries Ltd. null
  • Tel: +91-(22)-40999700, 9833720865
  • Fax: +91-(22)-40999777
  • Address: 901/904 Jagdamba Commercial Complex A/2, Near Movitime Theatre, Link Road, Malad (W), Mumbai, Maharashtra 400064, null,nullIndia
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57808-66-9 DOMPERIDONE, SOLID, 99%

  • DOMPERIDONE, SOLID, 99%
  • India Hritik Chemicals Corporation [Manufacturer]
  • Tel: 91-22-8206240,8210311
  • Fax: 91-22-8223847
  • Address: 109,Gokul Arcade,1st Floor, Near Garware polyster, Andheri-sahar Road, Ville Parle(E) Mumbai-400057 INDIA null,nullIndia
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57808-66-9 Domperidone

  • India Zenith Overseas null
  • Tel: 91-251-2474175
  • Address: 14/8,Vivekanand Society,Dombivli 421201,Maharashtra null,nullIndia
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57808-66-9 Domperidone

  • India Spansules Pharmatech Pvt. Ltd. null
  • Tel: +91-(40)-23061309, 23061982
  • Fax: +91-(40)-23061979
  • Address: Plot No.39,G-3,Srivenkateswara Towers, Bhagyanagar Colony, Opp.KPHB., Hyderabad, Andhra Pradesh 500 072, null,nullIndia
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57808-66-9 Domperidone

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References of 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-
benzimidazol-2-one
Title: Domperidone
CAS Registry Number: 57808-66-9
CAS Name: 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Synonyms: 5-chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone
Manufacturers' Codes: R-33812
Trademarks: Euciton (Roux-Ocefa); Evoxin (Sterling Winthrop); Gastronorm (Janssen); Mod (Irbi); Motilium (Janssen); Nauzelin (Janssen); Peridon (Italchimici); Peridys (Robapharm)
Molecular Formula: C22H24ClN5O2
Molecular Weight: 425.91
Percent Composition: C 62.04%, H 5.68%, Cl 8.32%, N 16.44%, O 7.51%
Literature References: A novel in vitro dopamine antagonist with antinauseant properties. Prepn: J. Vandenberk et al., DE 2632870; eidem, US 4066772 (1977, 1978 both to Janssen). Pharmacology: C. Ennis et al., J. Pharm. Pharmacol. 31, Suppl., 14P (1979). Gastrokinetic properties: J. M. Van Neuten et al., Life Sci. 23, 453 (1978). 3H-domperidone studies: M. P. Martres et al., ibid. 1781; M. Baudry et al., Arch. Pharmacol. 308, 231 (1979). Clinical studies: A. J. Reyntjens et al., Arzneim.-Forsch. 28, 1194 (1978); D. B. Wilson, J. W. Dundee, Anaesthesia 34, 765 (1979). Review of pharmacology, pharmacokinetics and therapeutic efficacy: R. N. Brogden et al., Drugs 24, 360-400 (1982).
Properties: Crystals from DMF/water, mp 242.5°.
Melting point: mp 242.5°
Therap-Cat: Antiemetic.
Keywords: Antiemetic; Dopamine Receptor Antagonist.