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CAS No 56287-74-2 , 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one

  • Name: 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one
  • Synonyms: HQ 495;Arofuto; Afloqualonum [INN-Latin]; BRN 0819769; Afloqualona [INN-Spanish]; Aroft; Afloqualon;6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one; 56287-74-2;
  • CAS Registry Number:
  • Melting Point: 195-196 ºC
  • Density: 1.31 g/cm3
  • Refractive index: 1.642
  • Safety Statements: Poison by ingestion and intraperitoneal routes. Moderately toxic by other routes. When heated to decomposition it emits toxic fumes of F− and NOx.
  • Molecular Weight: 283.300263
  • InchiKey: VDOSWXIDETXFET-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H14FN3O/c1-10-4-2-3-5-14(10)20-15(9-17)19-13-7-6-11(18)8-12
    (13)16(20)21/h2-8H,9,18H2,1H3
  • Molecular Formula: C16H14FN3O
  • Molecular Structure:CAS No:56287-74-2 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one
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56287-74-2 Afloqualone

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China ,China
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56287-74-2 Afloqualone

  • Afloqualone
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,China
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56287-74-2 AFLOQUALONE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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56287-74-2 Afloqualone

  • Afloqualone, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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56287-74-2 Afloqualone

  • Afloqualone, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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56287-74-2 Afloqualone

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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56287-74-2 Afloqualone

  • China China Langchem Inc. []
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, ,China
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56287-74-2 Afloqualone

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
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56287-74-2 4(3H)-Quinazolinone,6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-

  • China Shanghai chemrole co.,ltd [Manufacturers]
  • Tel: 021-50278900
  • Fax: 021-50278968
  • Address: No.6,bisheng road ,shanghai ,china ,ShanghaiChina
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56287-74-2 4(3H)-Quinazolinone,6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-

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References of 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one
Title: Afloqualone
CAS Registry Number: 56287-74-2
CAS Name: 6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
Synonyms: 6-amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone
Manufacturers' Codes: HQ-495
Trademarks: Arofuto (Tanabe)
Molecular Formula: C16H14FN3O
Molecular Weight: 283.30
Percent Composition: C 67.83%, H 4.98%, F 6.71%, N 14.83%, O 5.65%
Literature References: A centrally acting muscle relaxant. Prepn: I. Inoue et al., DE 2449113; eidem, US 3966731 (1975, 1976 to Tanabe); J. Tani et al., J. Med. Chem. 22, 95 (1979). Pharmacology: T. Ochiai, R. Ishida, Jpn. J. Pharmacol. 31, 491 (1981); 32, 427 (1982). Metabolism: N. Otsuka et al., J. Pharmacobio-Dyn. 5, S-59 (1982); S. Furuuchi et al., Drug Metab. Dispos. 11, 371 (1983).
Properties: Pale yellow prisms from 2-propanol, mp 195-196°. LD50 in mice (mg/kg): 315.1 i.p. (Tani).
Melting point: mp 195-196°
Toxicity data: LD50 in mice (mg/kg): 315.1 i.p. (Tani)
Therap-Cat: Muscle relaxant (skeletal).
Keywords: Muscle Relaxant (Skeletal).