Home > Name List By other > (6R,7R)-7-[[2-(3, 5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3, 4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia...

CAS No 56187-47-4 , (6R,7R)-7-[[2-(3,
5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,
4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
ene-2-carboxylic acid

  • Name: (6R,7R)-7-[[2-(3,
    5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,
    4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
    ene-2-carboxylic acid
  • Synonyms: Cefazedona [INN-Spanish]; Cefazedonum [INN-Latin]; Cefazedona;(6R,7R)-7-[[2-(3,
    5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,
    4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
    ene-2-carboxylic acid; Cefazedone [INN:BAN]; Cefazedonum; Refosporen; 56187-47-4;Refosporene;
  • CAS Registry Number:
  • Transport: 5kgs
  • Density: 1.78 g/cm3
  • Refractive index: 1.719
  • EINECS: 264-293-9
  • Molecular Weight: 548.4432
  • InchiKey: VTLCNEGVSVJLDN-MLGOLLRUSA-N
  • InChI: InChI=1S/C18H15Cl2N5O5S3/c1-7-22-23-18(33-7)32-6-8-5-31-16-12(15(28)25
    (16)13(8)17(29)30)21-11(26)4-24-2-9(19)14(27)10(20)3-24/h2-3,12,16H,
    4-6H2,1H3,(H,21,26)(H,29,30)/t12-,16-/m1/s1
  • Molecular Formula: C18H15Cl2N5O5S3
  • Molecular Structure:CAS No:56187-47-4 (6R,7R)-7-[[2-(3,<br />5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,<br />4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-<br />ene-2-carboxylic acid

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56187-47-4 Cefazedone acid

  • Product name:Cefazedone acid Chemical name: (6R,7R)-7-{[(3,5-Dichloro-4-oxopyridin-1(4H)-yl)acetyl]amino}-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CAS No.56187-47-4 Molecular for...
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  • China Pingyuan Sihuan Pharmaceutical Company [Manufacturer]
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  • Address: NO 2766 Yingxiu Road Jinan,ShandongChina

56187-47-4 CEFAZEDONE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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56187-47-4 Diclofenac Resinate

  • India JAI RADHE SALES []
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56187-47-4 Diclofenac Resinate

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56187-47-4 Cefazedone

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56187-47-4 Cefazedone Free Acid

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56187-47-4 CEFAZEDONE

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References of (6R,7R)-7-[[2-(3,
5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,
4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-
ene-2-carboxylic acid
Title: Cefazedone
CAS Registry Number: 56187-47-4
CAS Name: (6R,7R)-7-[[(3,5-Dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: 3-(5-methyl-1,3,4-thiadiazolyl-2-mercaptomethyl)-7-(3,5-dichloro-4-pyridon-1-ylacetamido)-3-cephem-4-carboxylic acid
Manufacturers' Codes: EMD-30087
Molecular Formula: C18H15Cl2N5O5S3
Molecular Weight: 548.44
Percent Composition: C 39.42%, H 2.76%, Cl 12.93%, N 12.77%, O 14.59%, S 17.54%
Literature References: Semi-synthetic cephalosporin antibiotic. Prepn: R. Gerike et al., DE 2345402; eidem, US 4153693 (1975, 1979 both to E. Merck, W. Ger.). See also eidem, DE 2621011, DE 2626026, DE 2627204 (all 1977 to E. Merck, W. Ger.), C.A. 88, 5093, 105383, 121213 (1978). Series of articles on prepn, in vitro and in vivo activity, kinetics, pharmacology, toxicology, and clinical trials: Arzneim.-Forsch. 29, 361-462 (1979). Toxicity data: M. von Eberstein et al., ibid. 424.
Properties: Crystals from acetonitrile.
 
Derivative Type: Sodium salt
CAS Registry Number: 63521-15-3
Trademarks: Refosporin (Merck KGaA)
Molecular Formula: C18H14Cl2N5NaO5S3
Molecular Weight: 570.43
Percent Composition: C 37.90%, H 2.47%, Cl 12.43%, N 12.28%, Na 4.03%, O 14.02%, S 16.86%
Properties: LD50 in mice, rats, rabbits, dogs (mg/kg): 6800, 4225, 3200, 3000 i.v. (von Eberstein).
Toxicity data: LD50 in mice, rats, rabbits, dogs (mg/kg): 6800, 4225, 3200, 3000 i.v. (von Eberstein)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.