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CAS No 55779-06-1 , Astromicin

  • Name: Astromicin
  • Synonyms: fortimicin;Astromicin;
  • CAS Registry Number:
  • Flash Point: 329.4°C
  • Boiling Point: 621.1°Cat760mmHg
  • Density: 1.31g/cm3
  • Safety Statements: Poison by subcutaneous and intravenous routes. Moderately toxic by intraperitoneal and intramuscular routes. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 329.4°C
  • Molecular Weight: 405.492
  • InChI: InChI=1/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1
  • Molecular Formula: C17H35N5O6
  • Molecular Structure:CAS No:55779-06-1 Astromicin
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55779-06-1 FORTIMICIN A, 85%(TLC)

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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55779-06-1 Astromicin

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55779-06-1 Astromicin sulphate

  • Astromicin sulphate, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,China
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55779-06-1 Fortimicin A

  • Fortimicin A, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,China
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55779-06-1 Astromicin

  • Astromicin, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,China
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55779-06-1 Astromicin

  • China Haihang Industry Co., Ltd. []
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, ,China
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55779-06-1 ASTROMICIN

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA ,China
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55779-06-1 Astromicin

  • United States Tecoland Corporation []
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, ,United States
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55779-06-1 Fortimicin

  • Fortimicin
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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55779-06-1 FORTIMICIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of Astromicin
Title: Fortimicins
Literature References: Aminoglycoside antibiotic complex produced by Micromonospora olivoasterospora. The main components, fortimicins A and B, both exhibit broad-spectrum antibacterial activity. Isoln of A: T. Nara et al., JP Kokai 75 29789 (to Kyowa); eidem, US 3976768 (1976 to Abbott). Isoln of B: eidem, DE 2418349 (1974 to Kyowa); eidem, US 3931400 (1976 to Abbott). Isoln and biological properties of A and B: eidem, J. Antibiot. 30, 533 (1977); physical and chromatographic properties: R. Okachi et al., ibid. 541. Structures of A and B: R. S. Egan et al., ibid. 552. In vitro activity: R. Girolami, J. S. Stamm, ibid. 564. Isoln and properties of minor components, fortimicins C, D, KE: M. Sugimoto et al., ibid. 32, 868 (1979). Synthesis of B: T. Suami, Y. Honda, Chem. Lett. 1980, 641; Y. Honda, T. Suami, Bull. Chem. Soc. Jpn. 55, 1156 (1982).
 
Derivative Type: Fortimicin A
CAS Registry Number: 55779-06-1
CAS Name: 4-Amino-1-[(aminoacetyl)methylamino]-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol
Synonyms: astromicin
Manufacturers' Codes: Abbott 44747
Molecular Formula: C17H35N5O6
Molecular Weight: 405.49
Percent Composition: C 50.35%, H 8.70%, N 17.27%, O 23.67%
Properties: White amorphous powder, mp >200° (dec). [a]D25 +87.5° (c = 0.1 in water). Sol in water and lower alcohols. Insol in organic solvents. LD50 (of the sulfate salt) in mice (mg/kg): 380 i.v.; 400 s.c. (Nara, 1977).
Melting point: mp >200° (dec)
Optical Rotation: [a]D25 +87.5° (c = 0.1 in water)
Toxicity data: LD50 (of the sulfate salt) in mice (mg/kg): 380 i.v.; 400 s.c. (Nara, 1977)
 
Derivative Type: Fortimicin B
CAS Registry Number: 54783-95-8
CAS Name: 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol
Molecular Formula: C15H32N4O5
Molecular Weight: 348.44
Percent Composition: C 51.70%, H 9.26%, N 16.08%, O 22.96%
Properties: White amorphous powder, mp 101-103°. [a]D25 +22.2° (c = 0.1 in water). Sol in water and lower alcohols. Insol in organic solvents.
Melting point: mp 101-103°
Optical Rotation: [a]D25 +22.2° (c = 0.1 in water)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Aminoglycosides.