Home > Name List By 2 > 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino] oxyethanamine

CAS No 54739-18-3 , 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]
oxyethanamine

  • Name: 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]
    oxyethanamine
  • Synonyms: Fluvoxaminum; Fluvoxaminum [INN-Latin];Floxyfral; Dumyrox; Dumirox; Fluvoxamina;2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]
    oxyethanamine; Maveral; Faverin;
  • CAS Registry Number:
  • Melting Point: 120-122.5 ºC
  • Flash Point: 177.9°C
  • Boiling Point: 370.6°C at 760 mmHg
  • Flash Point: 177.9°C
  • Molecular Weight: 318.33465
  • InchiKey: CJOFXWAVKWHTFT-XSFVSMFZSA-N
  • InChI: InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)
    15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+
  • Molecular Formula: C15H21F3N2O2
  • Molecular Structure:CAS No:54739-18-3 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]<br />oxyethanamine

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References of 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]
oxyethanamine
Title: Fluvoxamine
CAS Registry Number: 54739-18-3
CAS Name: (E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone O-(2-aminoethyl)oxime
Synonyms: 5-methoxy-4￠-(trifluoromethyl)valerophenone (E)-O-(2-aminoethyl)oxime
Molecular Formula: C15H21F3N2O2
Molecular Weight: 318.33
Percent Composition: C 56.60%, H 6.65%, F 17.90%, N 8.80%, O 10.05%
Literature References: Selective serotonin reuptake inhibitor (SSRI). Prepn: NL 7503310; H. B. A. Welle, V. Claassen, US 4085225 (1975, 1978 both to Philips-Duphar). Inhibition of 5-HT uptake: V. Claassen et al., Br. J. Pharmacol. 60, 505 (1977). HPLC determn in plasma: G. J. De Jong, J. Chromatogr. 183, 203 (1980). Series of articles on pharmacology, pharmacokinetics and clinical trials in depression: Br. J. Clin. Pharmacol. 15, Suppl. 3, 347S-450S (1983). Clinical trial in obsessive-compulsive disorder: L. M. Koran et al., J. Clin. Psychopharmacol. 16, 121 (1996). Review of clinical experience in depression: M. R. Ware, J. Clin. Psychiatry 58, Suppl. 5, 15-23 (1997).
 
Derivative Type: Maleate
CAS Registry Number: 61718-82-9
Manufacturers' Codes: DU-23000; MK-264
Trademarks: Dumirox (Solvay); Faverin (Solvay); Fevarin (Solvay); Floxyfral (Solvay); Luvox (Solvay); Maveral (Farmades)
Molecular Formula: C15H21F3N2O2.C4H4O4
Molecular Weight: 434.41
Percent Composition: C 52.53%, H 5.80%, F 13.12%, N 6.45%, O 22.10%
Properties: Crystals from acetonitrile, mp 120-121.5°. Freely sol in ethanol, chloroform; sparingly sol in water. Practically insol in diethyl ether.
Melting point: mp 120-121.5°
 
Therap-Cat: Antidepressant; antiobsessional.
Keywords: Antidepressant; Antiobsessional; Serotonin Uptake Inhibitor.