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CAS No 53716-49-7 , 2-(6-chloro-9H-carbazol-2-yl)propanoic acid

  • Name: 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
  • Synonyms: Rimadyl; Carprofenum; Imadyl;2-(6-chloro-9H-carbazol-2-yl)propanoic acid; 53716-49-7; Carprofene [INN-French]; Ridamyl; Carprofeno [INN-Spanish]; Carprofenum [INN-Latin];
  • CAS Registry Number:
  • Transport: UN 2811
  • Density: 1.42 g/cm3
  • Refractive index: 1.731
  • Water Solubility: 50mg/ml solution in ethanol gives a clear solution.
  • Safety Statements: R25
  • Hazard Symbols: T: Toxic;
  • EINECS: 258-712-4
  • Molecular Weight: 273.71428
  • InchiKey: PUXBGTOOZJQSKH-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14
    (11)6-9/h2-8,17H,1H3,(H,18,19)
  • Risk Statements: S45
  • Molecular Formula: C15H12ClNO2
  • Molecular Structure:CAS No:53716-49-7 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
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53716-49-7 CARPROFEN

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
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53716-49-7 Carprofen

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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53716-49-7 Carprofen

  • China Facus Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-6237-8411
  • Fax: +86-(574)-6237-8410
  • Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800, Ningbo,ZhejiangChina
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53716-49-7 Carprofen

  • Carprofen, 99%
  • China Tianjin Pharmacn Science Co., Ltd. [Manufacturer]
  • Tel: 86-22-23359620/ 86-13612042162 (mobile)
  • Fax: 86-22-23359620
  • Address: 1006 Sinochem Building, 707 Lianmeng RD, Shijiazhuang 050061, Hebei, China null,nullChina
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53716-49-7 carprofen

  • China KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: +86-23-8650081
  • Fax: +86-23-8650081
  • Address: 7F,Commercial Building, No.3 Nanping West Road,Nan null,nullChina
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53716-49-7 Carprofen

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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53716-49-7 Carprofen

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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53716-49-7 CARPROFEN

  • China Shanghai Sunwise Chemical Co., Ltd. [Manufacturer]
  • Tel: +86-21-64063188
  • Fax: +86-21-64062858
  • Address: Shanghai Sunwise Chemical Co., Ltd.
    7G, No 1235 Wuzhong Road
    Shanghai P.R.China null,nullChina
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53716-49-7 Carprofen

  • Carprofen
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
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53716-49-7 Carprofen

  • Carprofen
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
  • Fax: +91 79 30071176, 26574630
  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
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References of 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
Title: Carprofen
CAS Registry Number: 53716-49-7
CAS Name: 6-Chloro-a-methyl-9H-carbazole-2-acetic acid
Manufacturers' Codes: C-5720; Ro-20-5720/000
Trademarks: Imadyl (Roche); Rimadyl (Pfizer)
Molecular Formula: C15H12ClNO2
Molecular Weight: 273.71
Percent Composition: C 65.82%, H 4.42%, Cl 12.95%, N 5.12%, O 11.69%
Literature References: Prepn: L. Berger, A. J. Corraz, DE 2337340; eidem, US 3896145 (1974, 1975 both to Hoffmann-La Roche). Pharmacology: L. O. Randall, H. Baruth, Arch. Int. Pharmacodyn. 220, 94 (1976). Stereospecific assay and disposition: J. M. Kemmerer et al., J. Pharm. Sci. 68, 1274 (1979). Metabolism: F. Rubio et al., ibid. 69, 1245 (1980). Pharmacokinetic and clinical studies in gout: T. F. Yu, J. Perel, J. Clin. Pharmacol. 20, 347 (1980). Use in treatment of rheumatoid arthritis: S. Jalava, Scand. J. Rheumatol. 1983, Suppl. 48, 5-12. Review of pharmacology and clinical efficacy: W. M. O'Brien, G. F. Bagby, Pharmacotherapy 7, 16 (1987).
Properties: Cryst from chloroform, mp 197-198°. LD50 orally in mice: 400 mg/kg (Berger, Corraz).
Melting point: mp 197-198°
Toxicity data: LD50 orally in mice: 400 mg/kg (Berger, Corraz)
Therap-Cat: Anti-inflammatory.
Therap-Cat-Vet: Anti-inflammatory.
Keywords: Antigout; Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives.