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CAS No 518-61-6 , 2-(dimethylamino)-1-phenothiazin-10-ylethanone

  • Name: 2-(dimethylamino)-1-phenothiazin-10-ylethanone
  • Synonyms: Histantin richter; Dacemazina [Spanish]; Dacemazinum [Latin];Ahistan; Dimethylglycylphenothiazine; Dacemazine [INN];2-(dimethylamino)-1-phenothiazin-10-ylethanone;
  • CAS Registry Number:
  • Flash Point: 247°C
  • Boiling Point: 484.9°Cat760mmHg
  • Density: 1.246g/cm3
  • Refractive index: 1.648
  • Flash Point: 247°C
  • Molecular Weight: 284.37604
  • InchiKey: HKUCYAHWPVLPFN-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H16N2OS/c1-17(2)11-16(19)18-12-7-3-5-9-14(12)20-15-10-6-4-8-
    13(15)18/h3-10H,11H2,1-2H3
  • Molecular Formula: C16H16N2OS
  • Molecular Structure:CAS No:518-61-6 2-(dimethylamino)-1-phenothiazin-10-ylethanone

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518-61-6 Dacemazine

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References of 2-(dimethylamino)-1-phenothiazin-10-ylethanone
Title: Ahistan
CAS Registry Number: 518-61-6
CAS Name: 10-(Dimethylamino)acetyl-10H-phenothiazine
Synonyms: 10-(N,N-dimethylglycyl)phenothiazine; dacemazine
Molecular Formula: C16H16N2OS
Molecular Weight: 284.38
Percent Composition: C 67.58%, H 5.67%, N 9.85%, O 5.63%, S 11.28%
Literature References: Prepd from phenothiazine and chloroacetyl chloride, followed by treatment with dimethylamine: Cusic, US 2694705 (1954 to Searle).
Properties: Crystals, mp 144-145°.
Melting point: mp 144-145°
 
Derivative Type: Hydrochloride
Molecular Formula: C16H16N2OS.HCl
Molecular Weight: 320.84
Percent Composition: C 59.90%, H 5.34%, N 8.73%, O 4.99%, S 9.99%, Cl 11.05%
Properties: Crystals, mp 230-231°.
Melting point: mp 230-231°
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Phenothiazines.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.