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CAS No 3546-03-0 , 10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile

  • Name: 10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile
  • Synonyms: Cyamemazinum [INN-Latin]; Tercian; Cyamemazin; Cianatil;10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile; Kyamepromazine;Cyamepromazine; 3546-03-0; Cyamemazine [INN];
  • CAS Registry Number:
  • Density: 1.21 g/cm3
  • Refractive index: 1.654
  • EINECS: 222-594-2
  • Molecular Weight: 323.45514
  • InchiKey: SLFGIOIONGJGRT-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15
    (11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
  • Molecular Formula: C19H21N3S
  • Molecular Structure:CAS No:3546-03-0 10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile
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3546-03-0 Cyamemazine

  • Cyamemazine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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3546-03-0 Cyamemazine

  • Cyamemazine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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3546-03-0 CYAMEMAZINE-D3

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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3546-03-0 10H-Phenothiazine-2-carbonitrile,10-[3-(dimethylamino)-2-methylpropyl]-

  • China Huasheng Chemical Co., Ltd. [Manufacturers]
  • Tel: 86 519 85121086
  • Fax: 86 519 85125369
  • Address: Tangzhuang Industrial park, Yaotang, Jintan, Jiangsu Changzhou,JiangsuChina
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3546-03-0 CYAMEMAZINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 10-[3-(dimethylamino)-2-methylpropyl]phenothiazine-2-carbonitrile
Title: Cyamemazine
CAS Registry Number: 3546-03-0
CAS Name: 10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile
Synonyms: 2-cyano-10-(3-dimethylamino-2-methylpropyl)phenothiazine; 10-(3-dimethylamino-2-methylpropyl)-3-cyanophenothiazine; cyamepromazine
Manufacturers' Codes: RP-7204; TH-2602
Trademarks: Kyamepromazine; Cianatil; Tercian (Th?aplix)
Molecular Formula: C19H21N3S
Molecular Weight: 323.46
Percent Composition: C 70.55%, H 6.54%, N 12.99%, S 9.91%
Literature References: Prepn: Jacob, Robert, US 2877224 (1959 to Rh?ne-Poulenc). Synthesis: Craig et al., J. Org. Chem. 26, 1138 (1961). Biotransformation studies: Robinson, J. Pharm. Pharmacol. 18, 19 (1966). Chemistry: Kiger, Kiger, Ann. Pharm. Fr. 23, 489 (1965).
Properties: Yellow oil, bp0.2-0.5 205-220°; also reported as yellow powder, mp 89-96° (Kiger). Practically insol in water. Sol in ethanol and in organic solvents.
Melting point: mp 89-96° (Kiger)
Boiling point: bp0.2-0.5 205-220°
 
Derivative Type: Maleate
Molecular Formula: C23H25N3O4S
Molecular Weight: 439.53
Percent Composition: C 62.85%, H 5.73%, N 9.56%, O 14.56%, S 7.30%
Properties: Pale yellow plates from methanol-ethanol, mp 196-197° (Craig).
Melting point: mp 196-197° (Craig)
 
Therap-Cat: Antipsychotic.
Keywords: Antipsychotic; Phenothiazines.