Home > Name List By 2 > 2-[4-(1, 3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone

CAS No 37561-27-6 , 2-[4-(1,
3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone

  • Name: 2-[4-(1,
    3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone
  • Synonyms: EINECS 253-552-1; DSSTox_CID_26296; Fenoverinum [INN-Latin];Spasmopriv; Fenoverine [INN:DCF];2-[4-(1,
    3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone; Fenoverina [INN-Spanish]; NCGC00160678-01;
  • CAS Registry Number:
  • Flash Point: 360.1°C
  • Boiling Point: 671.8°Cat760mmHg
  • Density: 1.343g/cm3
  • Refractive index: 1.678
  • Flash Point: 360.1°C
  • EINECS: 253-552-1
  • Molecular Weight: 459.56
  • InchiKey: UBAJTZKNDCEGKL-UHFFFAOYSA-N
  • InChI: InChI=1S/C26H25N3O3S/c30-26(29-20-5-1-3-7-24(20)33-25-8-4-2-6-21(25)29)
    17-28-13-11-27(12-14-28)16-19-9-10-22-23(15-19)32-18-31-22/h1-10,15H,
    11-14,16-18H2
  • Molecular Formula: C26H25N3O3S
  • Molecular Structure:CAS No:37561-27-6 2-[4-(1,<br />3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone

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References of 2-[4-(1,
3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone
Title: Fenoverine
CAS Registry Number: 37561-27-6
CAS Name: 10-[[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]acetyl]-10H-phenothiazine
Synonyms: 10-[4-(3,4-dioxymethylenebenzyl)-1-piperazinylacetyl]phenothiazine; 10-[(4-piperonyl-1-piperazinyl)acetyl]phenothiazine
Trademarks: Spasmopriv (Paillusseau)
Molecular Formula: C26H25N3O3S
Molecular Weight: 459.56
Percent Composition: C 67.95%, H 5.48%, N 9.14%, O 10.44%, S 6.98%
Literature References: Piperonylpiperazine derivative with spasmolytic activity. Prepn: A. Buzas, R. Pierre, FR 2092639 (1972), C.A. 77, 140143p (1972). Pharmacology, clinical studies in gastrointestinal disorders, dysmenorrhea: R. Pierre, R. Roustan, Med. Interne 15, 49 (1980). In treatment of colon dysfunction: Claudon, Rev. Fr. Gastro-Enterol. 198, 31 (1984).
Properties: Crystals from isopropyl ether, mp 141-142°. LD50 in mice (g/kg): ~1.50 orally, ~2.50 i.p. (Buzas, Pierre).
Melting point: mp 141-142°
Toxicity data: LD50 in mice (g/kg): ~1.50 orally, ~2.50 i.p. (Buzas, Pierre)
Therap-Cat: Antispasmodic.
Keywords: Antispasmodic.