Home > Name List By other > (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3, 17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15, 16-dodeca...

CAS No 516-42-7 , (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,
17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,
16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one

  • Name: (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,
    17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,
    16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
  • Synonyms: 20alpha-Cortolone; a-Cortolone; AC1L4NQA; .alpha.-Cortolone; 516-42-7;Cortolon;(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,
    17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,
    16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one; 20.alpha.-Cortolone; alpha-Cortolone;
  • CAS Registry Number:
  • Flash Point: 309°C
  • Boiling Point: 564.1°Cat760mmHg
  • Density: 1.248g/cm3
  • Refractive index: 1.576
  • Flash Point: 309°C
  • Molecular Weight: 366.49166
  • InchiKey: JXCOSKURGJMQSG-AZQJGLEESA-N
  • InChI: InChI=1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,
    17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,17-18,22-23,25-26H,3-11H2,
    1-2H3/t12-,13-,14+,15+,17+,18-,19+,20+,21+/m1/s1
  • Molecular Formula: C21H34O5
  • Molecular Structure:CAS No:516-42-7 (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,<br />17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,<br />16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one

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516-42-7 A-CORTOLONE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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516-42-7 20S-CORTOLONE-D7

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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References of (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,
17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,
16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
Title: Cortolone
CAS Registry Number: 516-42-7
CAS Name: (3a,5b,20S)-3,17,20,21-Tetrahydroxypregnan-11-one
Synonyms: 3a,17a,20a,21-pregnanetetrol-11-one
Molecular Formula: C21H34O5
Molecular Weight: 366.49
Percent Composition: C 68.82%, H 9.35%, O 21.83%
Literature References: Isolated from human urine after administration of cortisone, hydrocortisone or ACTH: D. K. Fukushima et al., J. Biol. Chem. 212, 449 (1955). Synthesis: L. H. Sarett, J. Am. Chem. Soc. 71, 1169 (1949); A. H. Soloway et al., ibid. 76, 2941 (1954).
Properties: Crystals from acetone, mp 208-209°. [a]D25 +44° (c = 0.5 in ethanol); also reported as [a]D28 +34.2° (ethanol).
Melting point: mp 208-209°
Optical Rotation: [a]D25 +44° (c = 0.5 in ethanol); [a]D28 +34.2° (ethanol)
 
Derivative Type: 3,20,21-Triacetate
CAS Registry Number: 2638-46-2
Molecular Formula: C27H40O8
Molecular Weight: 492.60
Percent Composition: C 65.83%, H 8.18%, O 25.98%
Properties: Crystals from methanol, mp 214-216° (Fukushima); also reported as mp 213-214° (Sarett). [a]D28 +28° (ethanol); also reported as [a]D25 +18° (c = 1 in acetone).
Melting point: mp 214-216° (Fukushima); mp 213-214° (Sarett)
Optical Rotation: [a]D28 +28° (ethanol); [a]D25 +18° (c = 1 in acetone)