Home > Name List By other > (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3, 5-diiodophenyl]propanoic acid

CAS No 51-48-9 , (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,
5-diiodophenyl]propanoic acid

  • Name: (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,
    5-diiodophenyl]propanoic acid
  • Synonyms: Thyrax; Tetraiodothyronine;L-thyroxine; Thyreoideum; Thyroxinal; synthroid; Thyroxine iodine; Thyratabs; levothyroxine;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,
    5-diiodophenyl]propanoic acid; thyroxin;
  • CAS Registry Number:
  • Melting Point: 223 ºC (DEC.)
  • Flash Point: 302.3°C
  • Boiling Point: 576.3°Cat760mmHg
  • Density: 2.635g/cm3
  • Refractive index: 1.795
  • Alpha: -5 º (1N NAOH:ETOH 1:2)
  • Safety Statements: R20/21/22:Harmfulbyinhalation,incontactwithskinandifswallowed.;
  • Hazard Symbols: Xn:Harmful;
  • Flash Point: 302.3°C
  • EINECS: 200-101-1
  • Molecular Weight: 776.87002
  • InchiKey: XUIIKFGFIJCVMT-LBPRGKRZSA-N
  • InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)
    19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C15H11I4NO4
  • Molecular Structure:CAS No:51-48-9 (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,<br />5-diiodophenyl]propanoic acid
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51-48-9 L-Thyroxine

  • L-Thyroxine Synonyms: levothyroxine; l-t4; t4(hormone); o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin; o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; tetraiodothyronine CAS: 51-48-9 EINECS: 200-101-1 Assay: 99% min. USP30 Packing: 1 kg /foi...
  • Min. Order: 1000000000
  • FOB Price: USDfalse - false /
  • China Wuhan Yuancheng Gongchuang Technology Co.Ltd. [Manufacturer]
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  • 51-48-9 L-Thyroxine CAS:51-48-9

    • L-Thyroxine CAS:51-48-9 Product Name:L-Thyroxine Another Name:: 3,5,3',5'-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3',5'-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;o-(4-hyd...
    • Min. Order: 100
    • China Yuancheng Pharma Co., Ltd [Manufacturer]
    • Tel: 86-27-68886724
    • Fax: 86-27-88048077899
    • Address: Ycgsales@ycphar.Com Wuhan,HubeiChina

    51-48-9 L-Thyroxine

    • L-Thyroxine Synonyms: levothyroxine; l-t4; t4(hormone); o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin; o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; tetraiodothyronine CAS: 51-48-9 EINECS: 200-101-1 Assay: 99% min. USP30 Packing: 1 kg /foi...
    • Min. Order: 10
    • FOB Price: USDfalse - false /
    • China Guangzhou HuAo Chenical Co.Ltd [Trading Company]
    • Tel: 86-020-28165915
    • Address: 1102,Unit 16, Ocean Time guangzhou,GuangdongChina
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    51-48-9 L-Thyroxine

    • L-Thyroxine Synonyms: levothyroxine; l-t4; t4(hormone); o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin; o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine; tetraiodothyronine CAS: 51-48-9 EINECS: 200-101-1 Assay: 99% min. USP30 Packing: 1 kg /foi...
    • Min. Order: 98
    • FOB Price: USDfalse - false /
    • China Guangzhou Huao Biochemical Co.Ltd [Manufacturer, Distributor/Wholesaler]
    • Tel: 86-020-28165197
    • Address: 1102,unit 16, Ocean Time, Nansha District , Guangzhou City ,Guangdong Province,China Guangzhou,GuangdongChina
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    51-48-9 L-Thyroxine (T4) angel(at)health-gym(dot)com

    • L-Thyroxine (T4) Email: angel(at)health-gym(dot)com Skype: live:angel_11616 CAS: 51-48-9 Einecs No: 200-101-1 Purity : 99%min MF: C15H11I4NO4 MW: 776.87 Appearance :White Crystalline Solid Standard : USP30 Grade : Pharmaceutical Grade Storage: Shadin...
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    • China HK Globle Sino Ocean Dev. Co., Limited [Manufacturer]
    • Tel: 86-156-23704830
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    51-48-9 L-Thyroxine

    • Basic Info Product Name:L-Thyroxine Other Name:T4 Purity:98%min CAS No.:51-48-9 M.W.:776.87 M.F.:C15H11I4NO4 Assay:HPLC Melting Point:223oC Water Solubility:Insoluble Appearance:White powder Company profile: We are Wuhan Magic Biotechnology CO.Ltd in...
    • China Wuhan Magic Biotechnology CO.Ltd [Manufacturer, Trading Company]
    • Tel: 86-027-55234455
    • Address: Xiongchu Avenue No.209 Wuhan,HubeiChina
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    51-48-9 L-Thyroxine T4

    • Basic Info Product Name:L-Thyroxine Other Name:T4 Purity:98%min CAS No.:51-48-9 M.W.:776.87 M.F.:C15H11I4NO4 Assay:HPLC Melting Point:223oC Water Solubility:Insoluble Appearance:White powder Our Advantages: 1.Rich experience.Our company is a professi...
    • China Bettli Industry Limited [Manufacturer, Trading Company]
    • Tel: 86-852-99657666
    • Address: Kaiser Certre No. 18 Centre Street Hong Kong,HubeiChina
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    51-48-9 L-Thyroxine

    • Basic Info Product Name:L-Thyroxine Other Name:T4 Purity:98%min CAS No.:51-48-9 M.W.:776.87 M.F.:C15H11I4NO4 Assay:HPLC Melting Point:223oC Water Solubility:Insoluble Appearance:White powder Our Advantages: 1.Rich experience.Our company is a professi...
    • China Bettli Industry Limited [Manufacturer, Trading Company]
    • Tel: 86-852-99657666
    • Address: Kaiser Certre No. 18 Centre Street Hong Kong,HubeiChina
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    51-48-9 L-Thyroxine

    • 1, High quality with competitive price: 1)Standard: Enterprise Standard 2)All Purity is 99% 3)We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1)Parcel can be sent out in 24 hours after payment. ...
    • Min. Order: 1
    • China Wuhan?Yuancheng?Gongchuang?Technology?Co.Ltd. [Manufacturer]
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    • Address: No.496,Zhongshan?Road,?Wuhan,?Hubei,?China Wuhan,HubeiChina
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    51-48-9 T4 (CAS: 51-48-9)

    • Assay: 98% min. Packing: foil bag or tin. Appearance: white or off-white crystalline powder Usage: Pharmaceutical material, Steroid hormone, Anabolin. For disease-free testosterone replacement therapy, male menopause, impotence and other diseases tre...
    • Min. Order: 1000
    • China Hubei Yuancheng Pharmaceutical Co., Ltd. [Manufacturer]
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    • Address: No.496,Zhongshan Road, Wuhan 430064, Hubei, China Wuhan,HubeiChina
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    References of (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,
    5-diiodophenyl]propanoic acid
    Title: Thyroxine
    CAS Registry Number: 51-48-9
    CAS Name: O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine
    Synonyms: (-)-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]alanine; 3,5,3¢,5¢-tetraiodo-L-thyronine; levothyroxine; T4
    Molecular Formula: C15H11I4NO4
    Molecular Weight: 776.87
    Percent Composition: C 23.19%, H 1.43%, I 65.34%, N 1.80%, O 8.24%
    Literature References: One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone, TSH, q.v. Circulates in the serum bound to specific proteins, primarily thyroxine-binding globulin, transthyretin, and albumin. Deiodinated in peripheral tissues to the active metabolite, liothyronine, q.v. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. Isoln from thyroid: E. C. Kendall, J. Am. Med. Assoc. 64, 2042 (1915); idem, J. Biol. Chem. 39, 125 (1919). Structure: C. R. Harington, Biochem. J. 20, 293, 300 (1926). Synthesis: C. R. Harington, G. Barger, ibid. 21, 169 (1927); of naturally occurring L-form: J. R. Chalmers et al., J. Chem. Soc. 1949, 3424; of isomers and racemate: L. G. Ginger, P. Z. Anthony, US 2889363; US 2889364 (both 1959 to Baxter Labs.). Direct determn in serum by RIA: J. C. Nelson, R. T. Tomel, Clin. Chem. 34, 1737 (1988). Comprehensive description of levothyroxine sodium: A. Post, R. J. Warren, Anal. Profiles Drug Subs. 5, 225-281 (1976). Review of pharmacology: E. Sypniewski, Ann. Thorac. Surg. 56, S2-S8 (1993); of therapeutic use: A. D. Toft, N. Engl. J. Med. 331, 174-180 (1994). Review of thyroid physiology: D. A. Fisher, Clin. Chem. 42, 135-139 (1996); R. R. Cavalieri, Thyroid 7, 177-181 (1997).
    Properties: Crystals, dec 235-236°. [a]25546 -3.2° (0.66 g in 6.07 g of 0.5N NaOH and 13.03 g alc); [a]D20 -4.4° (3% in 0.13N NaOH in 70% EtOH).
    Optical Rotation: [a]25546 -3.2° (0.66 g in 6.07 g of 0.5N NaOH and 13.03 g alc); [a]D20 -4.4° (3% in 0.13N NaOH in 70% EtOH)
     
    Derivative Type: Sodium salt
    CAS Registry Number: 55-03-8
    Synonyms: Levothyroxine sodium
    Trademarks: Eferox (Wyeth); Eltroxin (GSK); Euthyrox (Merck KGaA); Levaxin (Nycomed); Levothroid (Forest); Levothyrox (Merck-Cl¢enot); Levoxyl (Jones); Oroxine (GSK); Soloxine (Virbac); Synthroid (Knoll); Thyro-Tabs (VET A MIX)
    Molecular Formula: C15H10I4NNaO4
    Molecular Weight: 798.85
    Percent Composition: C 22.55%, H 1.26%, I 63.54%, N 1.75%, Na 2.88%, O 8.01%
    Properties: Occurs as the hydrate. Triclinic crystals or cream-colored powder. Odorless, tasteless, somewhat hygroscopic. d420 2.381. [a]D20 -4.4° (c = 3 in 70% ethanol). Soly in water (25°): about 15 mg/100 ml. Sol in mineral acids and in solns of alkali hydroxides and carbonates. More sol in alcohol. Very slightly sol in chloroform, ether. pH of a satd water soln: 8.35 to 9.35.
    Optical Rotation: [a]D20 -4.4° (c = 3 in 70% ethanol)
    Density: d420 2.381
     
    Derivative Type: DL-Thyroxine
    CAS Registry Number: 300-30-1
    Properties: Needle-like crystals. Dec 231-233°. Insol in water, in alcohol, and in the other usual organic solvents, but in the presence of mineral acids or alkalies it dissolves in alcohol; sol in solns of the alkali hydroxides and in hot solns of the alkali carbonates.
     
    Derivative Type: D-Thyroxine
    CAS Registry Number: 51-49-0
    Synonyms: Dextrothyroxine
    Properties: Crystals, dec 237°. [a]21546 +2.97° (0.74 g in 6 g of 0.5N NaOH and 14 g of alcohol).
    Optical Rotation: [a]21546 +2.97° (0.74 g in 6 g of 0.5N NaOH and 14 g of alcohol)
     
    Derivative Type: D-Thyroxine sodium salt
    CAS Registry Number: 137-53-1
    Synonyms: Dextrothyroxine sodium
    Trademarks: Choloxin (Knoll); Debetrol (Sanofi); Dethyrona (Abbott); Dextroid (Baxter); Dynothel (Henning); Eulipos (Boehringer, Mann.)
     
    Therap-Cat: Thyroid hormone. Dextrothyroxine as antilipemic.
    Therap-Cat-Vet: Thyroid hormone.
    Keywords: Antihypothyroid; Thyroid Hormone.