Home > Name List By other > (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3, 5-diiodophenyl]methanone

CAS No 1951-25-3 , (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,
5-diiodophenyl]methanone

  • Name: (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,
    5-diiodophenyl]methanone
  • Synonyms: (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,
    5-diiodophenyl]methanone; Amiodaronum [INN-Latin]; Amiodarona; Aminodarone; Aratac; Amiodarona [INN-Spanish];Cordarone; Amjodaronum; Pacerone;
  • CAS Registry Number:
  • Melting Point: 156 deg C
  • Flash Point: 337.9°C
  • Boiling Point: 635.1°C at 760 mmHg
  • Density: 1.58 g/cm3
  • Safety Statements: R20/21/22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 337.9°C
  • EINECS: 217-772-1
  • Molecular Weight: 645.3116
  • InchiKey: IYIKLHRQXLHMJQ-UHFFFAOYSA-N
  • InChI: InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-
    15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,
    13-14H2,1-3H3
  • Risk Statements: S36
  • Molecular Formula: C25H29I2NO3
  • Molecular Structure:CAS No:1951-25-3 (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,<br />5-diiodophenyl]methanone

Related products

Search by region :

Select to

1951-25-3 Amiodarone

  • Amiodarone
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

1951-25-3 AMIODARONE TAB

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
Contact Supplier

1951-25-3 Methanone,(2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-

Contact Supplier

1951-25-3 Amiodarone Base

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
Contact Supplier

1951-25-3 Methanone,(2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
Contact Supplier

1951-25-3 Amiodarone Base

  • China Hangzhou Sage Chemical Co., Ltd. [Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, null,ZhejiangChina
Contact Supplier

1951-25-3 Amiodarone Base

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
Contact Supplier

1951-25-3 Amiodarone Base

  • China Haihang Industry Co., Ltd. null
  • Tel: +86-(531)-88032799
  • Fax: +86-(531)-85821093
  • Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100, null,nullChina
Contact Supplier

1951-25-3 Amiodarone Base

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
Contact Supplier

1951-25-3 Amiodarone

Contact Supplier

Select to

1/3
1 2 3 Next
References of (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,
5-diiodophenyl]methanone
Title: Amiodarone
CAS Registry Number: 1951-25-3
CAS Name: (2-Butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone
Synonyms: 2-butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone; 2-butyl-3-[3,5-diiodo-4-(b-diethylaminoethoxy)benzoyl]benzofuran
Molecular Formula: C25H29I2NO3
Molecular Weight: 645.31
Percent Composition: C 46.53%, H 4.53%, I 39.33%, N 2.17%, O 7.44%
Literature References: Benzofuran derivative with multiple electrophysiological effects. Prepn: FR 1339389; R. Tondeur, F. Binon, US 3248401 (1963, 1966 to Soc. Belge l'Azote Prod. Chim. Marly). Physicochemical properties: M. Bonati et al., J. Pharm. Sci. 73, 829 (1984). HPLC determn in plasma: M. De Smet, D. L. Massart, J. Pharm. Biomed. Anal. 6, 277 (1988). Comprehensive description: T. A. Plomp, Anal. Profiles Drug Subs. 20, 1-120 (1991). Review of pharmacology, clinical efficacy and safety: M. Chow, Ann. Pharmacother. 30, 637-643 (1996); B. N. Singh, Clin. Cardiol. 20, 608-618 (1997). Clinical trial in cardiac resuscitation: P. J. Kudenchuk et al., N. Engl. J. Med. 341, 871 (1999); to prevent atrial fibrillation: D. Roy et al., ibid. 342, 913 (2000).
 
Derivative Type: Hydrochloride
CAS Registry Number: 19774-82-4
Manufacturers' Codes: L-3428
Trademarks: Amiodar (Sanofi Winthrop); Ancaron (Taisho); Cordarex (Sanofi Winthrop); Cordarone (Wyeth); Ortacrone (Sanofi Winthrop); Pacerone (Upsher-Smith); Tachydaron (AWD); Trangorex (Sanofi Winthrop)
Molecular Formula: C25H29I2NO3.HCl
Molecular Weight: 681.77
Percent Composition: C 44.04%, H 4.44%, I 37.23%, N 2.05%, O 7.04%, Cl 5.20%
Properties: Crystalline powder, mp 156°. Also reported as crystals from acetone, mp 159 ±2° (Bonati). Soly at 25° (g/100ml): chloroform 44.51; methylene chloride 19.20; methanol 9.98; ethanol 1.28; benzene 0.65; tetrahydrofuran 0.60; acetonitrile 0.32; 1-octanol 0.30; ether 0.17; 1-propanol 0.13; water 0.07; hexane 0.03 petroleum ether 0.001. Sparingly sol in isopropanol; slightly sol in acetone, dioxane, and carbon tetrachloride. pH (5% soln) 3.4-3.9. pKa (25°C) 6.56 ±0.06. uv max (methanol): 208, 242 nm (E1%1cm 662 ±8, 623 ±10).
Melting point: mp 156°; mp 159 ±2° (Bonati)
pKa: pKa (25°C) 6.56 ±0.06
Absorption maximum: uv max (methanol): 208, 242 nm (E1%1cm 662 ±8, 623 ±10)
 
Therap-Cat: Antiarrhythmic (class III).
Keywords: Antiarrhythmic.