Home > Name List By 5 > 5-fluoro-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

CAS No 50-91-9 , 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

  • Name: 5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • Synonyms: Floxuridin; FUDR; Fluorodeoxyuridine; Deoxyfluorouridine;5-fluoro-1-[(2R,4S,
    5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 50-91-9;2'-Deoxy-5-fluorouridine; Fluoruridine deoxyribose; 5-Fluorodeoxyuridine;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 148-153 ºC
  • Density: 1.64 g/cm3
  • Refractive index: 1.608
  • Alpha: 35.9 º (C=1, WATER)
  • Safety Statements: R22;R36/37/38;R68
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 200-072-5
  • Molecular Weight: 246.192443
  • InchiKey: ODKNJVUHOIMIIZ-RRKCRQDMSA-N
  • InChI: InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,
    5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
  • Risk Statements: S26;S36/37/39
  • Molecular Formula: C9H11FN2O5
  • Molecular Structure:CAS No:50-91-9 5-fluoro-1-[(2R,4S,<br />5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
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50-91-9 1-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1H,3H)-dione

  • 1-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-methyltetrahydrofuran-2-yl]-5-fluoropyrimidine-2,4(1H,3H)-dione, 97
  • United Kingdom Atlantic Research Chemicals Ltd [Manufacturer]
  • Tel: +44-8707 746454
  • Fax: +44-8707 756455
  • Address: Atlantic Research Chemicals Ltd
    Unit A, Stratton View Business Park
    Holsworthy Road
    Stratton
    Bude
    Cornwall EX23 9NR
    UK null,nullUnited Kingdom
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50-91-9 2-Deoxy-5-fluorouridine

  • 2-Deoxy-5-fluorouridine
  • Hong kong Frapp's Pharma (Hongkong) Co.,Ltd [Manufacturer]
  • Tel: +852 8130 0917
  • Fax: +852 8130 0927
  • Address: Room 801,Mongkok Harbour Centre,638 Shanghai Street,Mongkok,Kowloon,Hongkang518001 MongkokHONG KONG Mongkok,nullHong kong
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50-91-9 Doxifluridine

  • Doxifluridine5'-Deoxy-5-fluorouridine
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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50-91-9 (+)-5-Fluoro-2'-deoxyuridine

  • (+)-5-Fluoro-2'-deoxyuridine
  • China Suzhou Rovathin Foreign Trade Co.,Ltd [Manufacturer]
  • Tel: 86-512-65816829/ 86-512-61978430
  • Fax: 86-512-65816839
  • Address: Suzhou Rovathin Foreign Trade Co.,Ltd
    (Sales Company of Affiliated Plant in China)
    Room 603, 327 of ShiZi Street,
    Suzhou, Jiangsu, China 215006 null,nullChina
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50-91-9 Floxuridine

  • Floxuridine, 99,00%
  • China Zeniview Chemistry Technology Co., Ltd. [Manufacturer]
  • Tel: +86-25-86088590
  • Fax: +86-25-85612276
  • Address: No.05,No.01 Hangzhongmen Dajie, Nanjing, China 210016 Nanjing CHINA 210016 NanjingCHINA Nanjing,nullChina
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50-91-9 A1147 2''-DEOXY-5-FLUORO-D-URIDINE

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK null,nullUnited Kingdom
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50-91-9 (+)-5-Fluoro-2'-deoxyuridine

  • (+)-5-Fluoro-2'-deoxyuridine
  • China Shanghai Synnad Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 86 21 5109 7911
  • Fax: 86 21 5109 7955
  • Address: B-5 Ecust Science Park, No. 18, Lane 1305, Hua Jing Road, Shanghai 200231 China Shanghai,ShanghaiChina
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50-91-9 2-Deoxy-5-Fluorouridine

  • 2-Deoxy-5-Fluorouridine
  • China Shenzhen sailing chemical Co.,Ltd [Manufacturer]
  • Tel: 86-755-26415005
  • Fax: 86-755-26412646
  • Address: 1-403 Bei tou hao yuan Nanxing Road Nanshan District Shenzhen, Guangdong 518051 shenzhenCHINA shenzhen,nullChina
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50-91-9 2'-Deoxy-5-fluorouridine

  • 2'-Deoxy-5-fluorouridine
  • United States RIA International [Manufacturer]
  • Tel: 19735811282
  • Fax: 19735811283
  • Address: 11 Melanie Lane #17 East Hanover 07936 NJ UNITED STATES NJ,nullUnited States
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50-91-9 Floxuridine

  • Floxuridine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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References of 5-fluoro-1-[(2R,4S,
5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Title: Floxuridine
CAS Registry Number: 50-91-9
CAS Name: 2¢-Deoxy-5-fluorouridine
Synonyms: 1-(2-deoxy-b-D-ribofuranosyl)-5-fluorouracil; 5-fluoro-2¢-deoxy-b-uridine
Manufacturers' Codes: NSC-27640
Trademarks: FUDR (Roche)
Molecular Formula: C9H11FN2O5
Molecular Weight: 246.19
Percent Composition: C 43.91%, H 4.50%, F 7.72%, N 11.38%, O 32.49%
Literature References: Prepn: Hoffer et al., J. Am. Chem. Soc. 81, 4112 (1959); Heidelberger, Duschinsky, US 2885396 (1959); Duschinsky et al., US 2970139 (1961); Hoffer, US 2949451; US 3041335 (1960, 1962 both to Hoffmann-La Roche). Structure: Lemieux, Hoffer, Can. J. Chem. 39, 110 (1961). Crystal and molecular structure: Harris, Diss. Abstr. 24, 4425 (1964); Harris, McIntyre, Biophys. J. 4, 203 (1964). Conformation of furanose ring in molecule: Sundaralingam, J. Am. Chem. Soc. 87, 599 (1965).
Properties: Crystals from butyl acetate, mp 150-151° (Hoffer, 1959); also reported as mp 145° (US 3041335). [a]D +37° (water), +48.6° (DMF). uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480).
Melting point: mp 150-151° (Hoffer, 1959); mp 145° (US 3041335)
Optical Rotation: [a]D +37° (water), +48.6° (DMF)
Absorption maximum: uv max (pH 7.2): 268 nm (e 7570); (pH 14): 270 nm (e 6480)
 
Derivative Type: a-Anomer
Synonyms: 1-(2-Deoxy-a-D-erythro-pentofuranosyl)-5-fluorouracil
Properties: Crystals from butyl acetate, mp 150-151°. [a]D25 -21° (c = 2 in water).
Melting point: mp 150-151°
Optical Rotation: [a]D25 -21° (c = 2 in water)
 
Therap-Cat: Antiviral; antineoplastic.
Keywords: Antineoplastic; Antimetabolites; Pyrimidine Analogs; Antiviral; Purines/Pyrimidinones.