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CAS No 50-12-4 , 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione

  • Name: 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
  • Synonyms: 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione; Mesantoin; Triantoin; Methylphenetoin;Methoin; Sedantoin; Insulton; Epiazin; Sedantoinal; Phenantoin;
  • CAS Registry Number:
  • Melting Point: 135-138 °C
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.154g/cm3
  • Safety Statements: Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: somnolence, hemorrhage, changes in teeth and supporting structures. Human mutation data reported. An experimental teratogen. An FDA proprietary drug used as an anticonvulsant. When heated to decomposition it emits toxic fumes of NOx.
  • Hazard Symbols: Xn
  • Flash Point: °C
  • EINECS: 200-012-8
  • Molecular Weight: 218.25176
  • InchiKey: GMHKMTDVRCWUDX-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,
    3H2,1-2H3,(H,13,16)
  • Molecular Formula: C12H14N2O2
  • Molecular Structure:CAS No:50-12-4 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione

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References of 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
Title: Mephenytoin
CAS Registry Number: 50-12-4
CAS Name: 5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
Synonyms: 5-ethyl-3-methyl-5-phenylhydantoin; 3-methyl-5,5-phenylethylhydantoin; "methyl hydantoin"; phenylethylmethylhydantoin; 3-ethylnirvanol; methoin
Trademarks: Insulton; Mesontoin; Mesantoin (Sandoz); Phenantoin; Sedantoinal (Sandoz); Gerot-Epilan (Gerot); Sacerno (EGYT)
Molecular Formula: C12H14N2O2
Molecular Weight: 218.25
Percent Composition: C 66.04%, H 6.47%, N 12.84%, O 14.66%
Literature References: Prepn: FR 769667; CH 166004 (both 1934 to Sandoz); CH 179692 (1935 to Sandoz). Pharmacology: I. A. Dzhagatspanyan et al., Pharm. Chem. J. 25, 181 (1991).
Properties: Crystals, mp 136-137°. Insol in water. Forms a water-soluble sodium salt which has an alkaline reaction. LD50 i.p. in mice: 300 mg/kg (Dzhagatspanyan).
Melting point: mp 136-137°
Toxicity data: LD50 i.p. in mice: 300 mg/kg (Dzhagatspanyan)
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant.