Home > Name List By t > Triptolide

CAS No 38748-32-2 , Triptolide

  • Name: Triptolide
  • Synonyms: Triptolide;Triptolide 95%;
  • CAS Registry Number:
  • Density: 1.48 g/cm3
  • Refractive index: 1.647
  • Water Solubility: DMSO: soluble
  • Safety Statements: Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Molecular Weight: 360.41
  • InChI: InChI=1/C20H24O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14,16,22H,4-7H2,1-3H3/t11-,12-,13-,14-,16+,17-,18-,19+,20+/m0/s1
  • Molecular Formula: C20H24O6
  • Molecular Structure:CAS No:38748-32-2 Triptolide
Search by region :

Select to

38748-32-2 Triptolide

  • Triptolide Synonym: PG490;TRIPTOLIDE;TRIPTOLIDE, TRIPTERYGIUM WILFORDII;,7as,7bs,8as,8bs)-;8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-,(3bs,4as,5as,6r,6ar;triptolid;TRIPTOLIDE TLC; CAS: 38748-32-2 Assay: NLT99% M.F: C20H24O6 M.W: 360.4 ...
  • Min. Order: 500
  • China Hubei Gongchuang Group [Manufacturer, Trading Company]
  • Tel: 86-027-15927298986
  • Address: Zhongshan Road Wuchang Wuhan,HubeiChina
Contact Supplier

38748-32-2 Triptolide98%

  • Packaging & Delivery Packaging Detail:25Kg/Fiber Drum, double plastic bag inside, with carton outside. 1Kg/Bag, aluminum foil bag vacuum packing. Delivery Detail:within 5 days after receiving payment Specifications LEI GONG TENG/Thunder god vine extr...
  • China Changsha Luyuan Bio-Tech.,Ltd. [Manufacturer, Trading Company, Association]
  • Tel: 86-731-83392876
  • Fax: 86-731-82526361
  • Address: 2nd Floor ,4 Building Xiangshuyuan,No. 8 Lutian Road, High-tech Developement District Changsha,HunanChina
Contact Supplier

flyger
  • i
  • 38748-32-2 Triptolide

    • English Name: Triptolide Molecular Formula: C20H24O6 Molecular Weight: 360.41 CAS: 38748-32-2 Purity: HPLC≥98% Package: 10g 20g 50g 100g, or customized. Appearance: white crystal Source: Xylem without bark or Whole Tripterygium wilfordii Hook. f. So...
    • Min. Order: 0
    • China Sichuan Weikeqi Biological Technology Co., Ltd [Other]
    • Tel: 86-028-81700200
    • Fax: 86-028-81705658
    • Address: Qingjiang Zhonglu 63 chengdu,SichuanChina

    38748-32-2 TRIPTOLIDE 95%

    • Germany CHEMOS GmbH [Manufacturer]
    • Tel: 0049 9402/9336 0
    • Fax: 0049 9402/9336 13
    • Address: CHEMOS GmbH
      Werner-von-Siemensstr. 3
      93128 Regenstauf
      Germany ,Germany
    Contact Supplier

    38748-32-2 TRIPTOLIDE

    • Germany Cfm Oskar Tropitzsch [Manufacturer]
    • Tel: +49-9231-9619-0
    • Fax: +49-9231-9619-60
    • Address: Cfm Oskar Tropitzsch
      Waldershofer Str. 49-51
      95615 Marktredwitz
      Germany ,Germany
    Contact Supplier

    38748-32-2 triptolide

    Contact Supplier

    38748-32-2 Triptolide

    • China Kouting Chemical Co.,Ltd [Importer/Exporter]
    • Tel: +86-(21)-58116473
    • Fax: +86-(21)-61094103
    • Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318, shanghai,shanghaiChina
    Contact Supplier

    38748-32-2 TRIPTOLIDE(P)

    • United States ChromaDex Inc. [Manufacturer]
    • Tel: 949-419-0288
    • Fax: 949-419-0294
    • Address: ChromaDex Inc.
      10005 Muirlands Blvd. Suite G - First Floor
      Irvine, CA 92618 ,United States
    Contact Supplier

    38748-32-2 triptolide

    Contact Supplier

    38748-32-2 triptolide

    Contact Supplier

    Select to

    References of Triptolide
    Title: Triptolide
    CAS Registry Number: 38748-32-2
    CAS Name: (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
    Synonyms: PG490
    Molecular Formula: C20H24O6
    Molecular Weight: 360.40
    Percent Composition: C 66.65%, H 6.71%, O 26.64%
    Literature References: Diterpenoid triepoxide with immunosuppressant and antitumor properties; isolated from the Chinese medicinal herb, Tripterygium wilfordii Hook. f., Celastraceae. Isoln and structure determn: S. M. Kupchan et al., J. Am. Chem. Soc. 94, 7194 (1972). Synthesis of racemate: R. S. Buckanin et al., ibid. 102, 1200 (1980); of naturally occurring (-)-form: D. Yang et al., ibid. 121, 5579 (1999). HPLC and SPE determn in Tripterygium root extracts: A. M. Brinker, I. Raskin, J. Chromatogr. A 1070, 65 (2005). Animal studies of male antifertility effects: A. P. S. Hikim et al., J. Androl. 21, 431 (2000); P. N. Huynh et al., ibid. 689. Mechanistic studies of apoptotic and antitumor activities: W.-T. Chang et al., J. Biol. Chem. 276, 2221 (2001); T. M. Kiviharju et al., Clin. Cancer Res. 8, 2666 (2002); S. J. Leuenroth, C. M. Crews, Chem. Biol. 12, 1259 (2005). Review of anti-inflammatory and immunosuppressive properties: B. J. Chen, Leuk. Lymphoma 42, 253-265 (2001).
    Properties: mp 226-227°. [a]D25 -154° (c = 0.369 in CH2Cl2). uv max (ethanol): 218 nm (e 14000). Sol in DMSO, ethanol. LD50 i.p. in mice: 1.93 mg/kg (Chen).
    Melting point: mp 226-227°
    Optical Rotation: [a]D25 -154°
    Absorption maximum: uv max (ethanol): 218 nm (e 14000)
    Toxicity data: LD50 i.p. in mice: 1.93 mg/kg (Chen)
     
    Derivative Type: 14-Succinyl triptolide sodium salt
    CAS Registry Number: 195883-09-1
    Synonyms: PG490-88
    Molecular Formula: C24H27NaO9
    Molecular Weight: 482.46
    Percent Composition: C 59.75%, H 5.64%, Na 4.77%, O 29.85%
    Literature References: Semi-synthetic water soluble prodrug. Prepn: Y. M. Qi, J. H. Musser, US 5663335 (1997 to Pharmagenesis). Animal model studies of prevention of graft-vs-host disease: B. J. Chen et al., Transplantation 70, 1442 (2000); of antitumor effects: J. M. Fidler et al., Mol. Cancer Ther. 2, 855 (2003); of allograft survival in organ transplantation: F. Pan et al., Transplant. Proc. 37, 134 (2005).