Home > Name List By other > [(2R,3R,4S,5R)-2-hydroxy-5-[(2S,3R,4S,5R)-5-hydroxy-3, 4-disulfooxyoxan-2-yl]oxy-3-sulfooxyoxan-4-yl] hydrogen sulfate

CAS No 37300-21-3 , [(2R,3R,4S,5R)-2-hydroxy-5-[(2S,3R,4S,5R)-5-hydroxy-3,
4-disulfooxyoxan-2-yl]oxy-3-sulfooxyoxan-4-yl] hydrogen sulfate

  • Name: [(2R,3R,4S,5R)-2-hydroxy-5-[(2S,3R,4S,5R)-5-hydroxy-3,
    4-disulfooxyoxan-2-yl]oxy-3-sulfooxyoxan-4-yl] hydrogen sulfate
  • Synonyms: Elmiron; Polypentose sulfate; Xylan; hydrogen sulfate; Pentosan sulfuric polyester; UNII-F59P8B75R4; 37300-21-3; pentosan polysulfate;[(2R,3R,4S,5R)-2-hydroxy-5-[(2S,3R,4S,5R)-5-hydroxy-3,
    4-disulfooxyoxan-2-yl]oxy-3-sulfooxyoxan-4-yl] hydrogen sulfate; AC1L1YAW;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 2.26g/cm3
  • Flash Point: °C
  • Molecular Weight: 602.49732
  • InchiKey: FCCNSUIJIOOXEZ-SJYYZXOBSA-N
  • InChI: InChI=1S/C10H18O21S4/c11-3-1-26-10(8(31-35(22,23)24)5(3)28-32(13,
    14)15)27-4-2-25-9(12)7(30-34(19,20)21)6(4)29-33(16,17)18/h3-12H,1-2H2,
    (H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)/t3-,4-,5+,6+,7-,8-,9-,
    10+/m1/s1
  • Molecular Formula: C10H18O21S4
  • Molecular Structure:CAS No:37300-21-3 [(2R,3R,4S,5R)-2-hydroxy-5-[(2S,3R,4S,5R)-5-hydroxy-3,<br />4-disulfooxyoxan-2-yl]oxy-3-sulfooxyoxan-4-yl] hydrogen sulfate

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References of [(2R,3R,4S,5R)-2-hydroxy-5-[(2S,3R,4S,5R)-5-hydroxy-3,
4-disulfooxyoxan-2-yl]oxy-3-sulfooxyoxan-4-yl] hydrogen sulfate
Title: Pentosan Polysulfate
CAS Registry Number: 37300-21-3
CAS Name: Xylan hydrogen sulfate
Synonyms: xylan polysulfate
Manufacturers' Codes: CB-8061
Literature References: Semi-synthetic sulfated polyanion composed of b-D-xylopyranose residues with properties similar to heparin, q.v. Mol wt ranges from 1500 to 5000. Prepn: CH 293566 (1953 to Wander), C.A. 49, 1787h (1955). Anticoagulant activity: B. Paramelle, Therapie 17, 719 (1962); J.-B., Dureux et al., ibid. 19, 879 (1964). Pharmacokinetics: R. Taugner et al., Arch. Int. Pharmacodyn. 189, 250 (1971). Effects on aggregation of human blood platelets: G. Kindness et al., Thromb. Res. 16, 97 (1979). Comparison of pentosan polysulfate with heparin: C. Soria et al., ibid. 19, 455 (1980); M. Ryde et al., ibid. 23, 435 (1981); A.-M. Fischer et al., Thromb. Haemostasis 47, 104, 109 (1982). Mechanism of antiadherence activity in urinary bladder: C. L. Parsons et al., Science 208, 605 (1980); eidem, Infect. Immun. 27, 876 (1980). Clinical trials in interstitial cystitis: A. Fritjofsson et al., J. Urol. 138, 508 (1987); S. G. Mulholland et al., Urology 6, 552 (1990).
 
Derivative Type: Sodium salt
CAS Registry Number: 37319-17-8
Synonyms: Sodium pentosan polysulfate; sodium xylan polysulfate
Trademarks: Cartrophen (Univet); Elmiron (Baker Norton); Fibrase (SK & F); Fibrezym (Bene-Arzneimittel); Hémoclar (Sanofi Winthrop); SP-54 (Bene-Chemie); Thrombocid (Bene-Chemie)
Properties: White odorless powder, slightly hygroscopic. [a]D20 -57°. pH of 10% aq soln ~6.0. nD20 of 10% aq soln: 1.344. Sol in water.
Optical Rotation: [a]D20 -57°
Index of refraction: nD20 of 10% aq soln: 1.344
 
Therap-Cat: In treatment of interstitial cystitis; antithrombotic.
Therap-Cat-Vet: Anti-inflammatory.
Keywords: Anticoagulant.