Home > Name List By 7 > 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1, 4-benzodiazepine-2-thione

CAS No 36735-22-5 , 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,
4-benzodiazepine-2-thione

  • Name: 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,
    4-benzodiazepine-2-thione
  • Synonyms: 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,
    4-benzodiazepine-2-thione; Selepam; Quazium; Oniria; Dormalin;Doral; Cetrane; Prosedar; Quazapam; Quazepamum [INN-Latin];
  • CAS Registry Number:
  • Transport: 3249
  • Density: 1.42 g/cm3
  • Refractive index: 1.595
  • EINECS: 253-179-4
  • Molecular Weight: 386.794253
  • InchiKey: IKMPWMZBZSAONZ-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-
    8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2
  • Molecular Formula: C17H11ClF4N2S
  • Molecular Structure:CAS No:36735-22-5 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,<br />4-benzodiazepine-2-thione

Related products

Search by region :

Select to

36735-22-5 Quazepam

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

36735-22-5 Quazepam

  • China Taizhou Crene Chempharm Co., Ltd. null
  • Tel: +86-(576)-88813233
  • Fax: +86-(576)-88670057
  • Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000, null,nullChina
Contact Supplier

36735-22-5 2H-1,4-Benzodiazepine-2-thione,7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-

  • Russia P&M-Invest [Manufacturers]
  • Tel: +7-495-1356494
  • Fax: +7-495-1356509
  • Address: Moscow, Vavilova str.28, Russia Moscow,MoscowRussia
Contact Supplier

36735-22-5 2H-1,4-Benzodiazepine-2-thione,7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-

Contact Supplier

36735-22-5 2H-1,4-Benzodiazepine-2-thione,7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-

  • United States Tosoh USA, Inc. [Manufacturers]
  • Tel: +1-614-2774348
  • Fax: +1-614-8758066
  • Address: 3600 Gantz Road, Grove City, OH 43123 null,nullUnited States
Contact Supplier

36735-22-5 QUAZEPAM

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,
4-benzodiazepine-2-thione
Title: Quazepam
CAS Registry Number: 36735-22-5
CAS Name: 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione
Manufacturers' Codes: Sch-16134
Trademarks: Doral (Wallace); Dormalin (Schering-Plough); Oniria (Lifepharma); Prosedar (Schering-Plough); Quazium (Schering); Selepam (Schering-Plough)
Molecular Formula: C17H11ClF4N2S
Molecular Weight: 386.79
Percent Composition: C 52.79%, H 2.87%, Cl 9.17%, F 19.65%, N 7.24%, S 8.29%
Literature References: Benzodiazepine hypnotic. Prepn: M. Steinman, DE 2138773; idem, US 3845039 (1972, 1974 both to Schering Corp.); M. Steinman et al., J. Med. Chem. 16, 1354 (1973). Pharmacology: A. Barnett et al., Arzneim.-Forsch. 32, 1452 (1982); E. Ongini et al., ibid. 1456. GC determn in plasma: J. M. Hilbert et al., J. Pharm. Sci. 73, 516 (1984). Pharmacokinetics: M. Chung et al., Clin. Pharm. Ther. 35, 520 (1984). Metabolism: N. Zampaglione et al., Drug Metab. Dispos. 13, 25 (1985). Clinical trials in insomnia: J. W. Goethe, G. Kader, Curr. Ther. Res. 32, 150 (1982); M. Mamelak et al., J. Clin. Pharmacol. 24, 65 (1984). Toxicology: H. E. Black et al., Arzneim.-Forsch. 37, 906 (1987).
Properties: Crystals from methylene chloride-hexane, mp 137.5-139°. LD50 in mice (mg/kg): >1370 i.v., >5000 orally (Orgini). LD50 in male, female mice, rats (mg/kg): 845, 921, 3072, 2749 i.p. (Black).
Melting point: mp 137.5-139°
Toxicity data: LD50 in mice (mg/kg): >1370 i.v., >5000 orally (Orgini); LD50 in male, female mice, rats (mg/kg): 845, 921, 3072, 2749 i.p. (Black)
NOTE: This is a controlled substance (depressant): 21 CFR, 1308.14.
Therap-Cat: Sedative, hypnotic.
Keywords: Sedative/Hypnotic; Benzodiazepine Derivatives.