Home > Name List By 1 > 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1, 3]oxazolo[3,2-d][1,4]benzodiazepin-6-one

CAS No 27060-91-9 , 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,
3]oxazolo[3,2-d][1,4]benzodiazepin-6-one

  • Name: 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,
    3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
  • Synonyms: BRN 1092501;Flutazolam [INN:JAN]; Flutazolamum [INN-Latin];10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,
    3]oxazolo[3,2-d][1,4]benzodiazepin-6-one; MS-4101; 27060-91-9;
  • CAS Registry Number:
  • Flash Point: 317.8°C
  • Boiling Point: 601.9°Cat760mmHg
  • Density: 1.47g/cm3
  • Refractive index: 1.672
  • Safety Statements: Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F−, Cl−, and NOx.
  • Flash Point: 317.8°C
  • Molecular Weight: 376.809223
  • InchiKey: WMFSSTNVXWNLKI-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H18ClFN2O3/c20-13-5-6-17-15(11-13)19(14-3-1-2-4-16(14)21)22
    (8-10-26-19)12-18(25)23(17)7-9-24/h1-6,11,24H,7-10,12H2
  • Molecular Formula: C19H18ClFN2O3
  • Molecular Structure:CAS No:27060-91-9 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,<br />3]oxazolo[3,2-d][1,4]benzodiazepin-6-one

Related products

Select to

27060-91-9 Flutazolam

  • Flutazolam, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

27060-91-9 Flutazolam

  • Flutazolam, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

27060-91-9 Flutazolam

Contact Supplier

27060-91-9 Flutazolam

  • Flutazolam, 99%
  • China Tianjin Pharmacn Science Co., Ltd. [Manufacturer]
  • Tel: 86-22-23359620/ 86-13612042162 (mobile)
  • Fax: 86-22-23359620
  • Address: 1006 Sinochem Building, 707 Lianmeng RD, Shijiazhuang 050061, Hebei, China null,nullChina
Contact Supplier

27060-91-9 Flutazolam

  • Flutazolam
  • China Hallopharma [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,nullChina
Contact Supplier

27060-91-9 Flutazolam

  • Flutazolam
  • China Inter-Chemical [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,nullChina
Contact Supplier

Select to

1/1
References of 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,
3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
Title: Flutazolam
CAS Registry Number: 27060-91-9
CAS Name: 10-Chloro-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
Manufacturers' Codes: MS-4101; Ro-7-6102
Trademarks: Coreminal (Mitsui)
Molecular Formula: C19H18ClFN2O3
Molecular Weight: 376.81
Percent Composition: C 60.56%, H 4.81%, Cl 9.41%, F 5.04%, N 7.43%, O 12.74%
Literature References: Tricyclic benzodiazepine deriv. Prepn: BE 765253; M. E. Derieg et al., US 3905956 (1971, 1975 both to Hoffmann-La Roche). Physicochemical properties: A. Ito et al., Iyakuhin Kenkyu 9, 787 (1978), C.A. 89, 169013e (1979). Psychopharmacological profile: T. Mitsushima, S. Ueki, Folia Pharmacol. Jpn. 74, 959 (1978), C.A. 90, 180083u (1979). Toxicological studies: K. Ishimura et al., Oyo Yakuri 15, 1081 (1978); eidem, ibid. 16, 693 (1978), C.A. 90, 16379z, 145909p (1979).
Properties: White prisms from toluene, mp 142-147°. pKa 5.40. Freely sol in chloroform, ethanol. Moderately sol in acetone, benzene, methanol. Practically insol in water.
Melting point: mp 142-147°
pKa: pKa 5.40
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Benzodiazepine Derivatives.