Home > Name List By other > [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl pyridine-3-carboxylate

CAS No 27959-26-8 , [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl
pyridine-3-carboxylate

  • Name: [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl
    pyridine-3-carboxylate
  • Synonyms: Cholexamine; K 31;[2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl
    pyridine-3-carboxylate; 27959-26-8; Nicomolol; K 31 (pharmaceutical); EINECS 248-748-9; Nicomolum [INN-Latin]; Cholexamin;
  • CAS Registry Number:
  • Flash Point: 415.4°C
  • Boiling Point: 763.3°Cat760mmHg
  • Density: 1.316g/cm3
  • Refractive index: 1.596
  • Safety Statements: Mildly toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. An anticholesteremic agent that reduces the blood cholesterol level. See also ESTERS.
  • Flash Point: 415.4°C
  • EINECS: 248-748-9
  • Molecular Weight: 640.63928
  • InchiKey: VRAHPESAMYMDQI-UHFFFAOYSA-N
  • InChI: InChI=1S/C34H32N4O9/c39-28(24-6-1-12-35-16-24)44-20-33(21-45-29(40)25-7-
    2-13-36-17-25)10-5-11-34(32(33)43,
    22-46-30(41)26-8-3-14-37-18-26)23-47-31(42)27-9-4-15-38-19-27/h1-4,6-9,
    12-19,32,43H,5,10-11,20-23H2
  • Molecular Formula: C34H32N4O9
  • Molecular Structure:CAS No:27959-26-8 [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl<br />pyridine-3-carboxylate

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27959-26-8 Nicomol

  • Nicomol, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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27959-26-8 NICOMOL

  • China Unispec Chemicals Co. [Manufacturer]
  • Tel: +86 25-52347273/ +86 25-51570518
  • Fax: +86 25-52337971
  • Address: Unispec Chemicals Co.
    Technology Building,
    No.5 New Model Road,
    Nanjing, China P.C.:210009 null,nullChina
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27959-26-8 3-Pyridinecarboxylicacid, 1,1',1'',1'''-[(2-hydroxy-1,3-cyclohexanediylidene)tetrakis(methylene)]ester

  • China BJ-MDS Biochem-Pharm Co., Ltd. [Manufacturers]
  • Tel: 0086-10-62170771, 0086-0-13801275483
  • Fax: 0086-10-62170771
  • Address: Suite 512, Commercial building B, No. 19, Dahuisi Road, Haidian District, Beijing, China 100081 Beijing,BeijingChina
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27959-26-8 NICOMOL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of [2-hydroxy-1,3,3-tris(pyridine-3-carbonyloxymethyl)cyclohexyl]methyl
pyridine-3-carboxylate
Title: Nicomol
CAS Registry Number: 27959-26-8
CAS Name: 3-Pyridinecarboxylic acid (2-hydroxy-1,3-cyclohexanediylidene)tetrakis(methylene) ester
Synonyms: nicotinic acid 1,1,3,3-tetraester with 2-hydroxy-1,1,3,3-cyclohexanetetramethanol; 2-hydroxycyclohexane-1,1,3,3-tetramethanol tetraester with nicotinic acid; tetranicotinic acid 2-hydroxycyclohexa-1,1,3,3-tetramethyl ester; 2,2,6,6-tetrakis(hydroxymethyl)-1-cyclohexanol 2,2,6,6-tetranicotinate; nicotinic acid 2-hydroxy-1,3-cyclohexanediylidenetetrakismethylene ester; 2,2,6,6-tetrakis(nicotinoyloxymethyl)cyclohexanol
Trademarks: K-31 (Kyorin); Cholexamin (Kyorin)
Molecular Formula: C34H32N4O9
Molecular Weight: 640.64
Percent Composition: C 63.74%, H 5.03%, N 8.75%, O 22.48%
Literature References: Prepn: BE 658422 corresp to Irikura et al., US 3299077 (1965 and 1967 to Kyorin). Hypocholesterolemic action studies: Aso et al., J. Atheroscler. Res. 10, 391 (1969). Acute toxicity data: T. Sugawara et al., Oyo Yakuri 14, 741 (1977), C.A. 88, 131005v (1977). Review: Jpn. Med. Gaz. 8(8), 9 (1971).
Properties: Crystals from dilute acetic acid, mp 177-180°. Practically odorless and tasteless. One gram is sol in 3 ml 1N HCl and 10 ml chloroform. Slightly sol in water, ethanol and ether. LD50 in mice, male and female rats (g/kg): >10, 15, <10 orally; >5, >2.5, >2.5 i.p. (Sugawara).
Melting point: mp 177-180°
Toxicity data: LD50 in mice, male and female rats (g/kg): >10, 15, <10 orally; >5, >2.5, >2.5 i.p. (Sugawara)
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Nicotinic Acid Derivatives.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.