Title: Methyl Nicotinate
CAS Registry Number: 93-60-7
CAS Name: 3-Pyridinecarboxylic acid methyl ester
Synonyms: nicotinic acid methyl ester
Trademarks: Midalgan
Molecular Formula: C7H7NO2
Molecular Weight: 137.14
Percent Composition: C 61.31%, H 5.14%, N 10.21%, O 23.33%
Literature References: Obtained by passing HCl gas into a hot methanol soln of nicotinic acid: Engler,
Ber. 27, 1787 (1894); by treatment with tetramethylammonium hydroxide in methanol: Prelog, Piantanida,
Z. Physiol. Chem. 244, 56 (1936); by heating a mixture of sulfuric acid, selenium and quinoline, followed by refluxing with methanol: Kaufman,
J. Am. Chem. Soc. 67, 497 (1945); from nicotinyl chloride hydrochloride and methanol in pyridine: Charonnat
et al., Bull. Soc. Chim. Fr. 1948, 1014.
Properties: Crystals, mp 39°. bp760 209°; bp3 70-72°. Soluble in water, alcohol, benzene.
Melting point: mp 39°
Boiling point: bp760 209°; bp3 70-72°
Therap-Cat: Rubefacient.