Home > Name List By d > Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-

CAS No 24219-97-4 , Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-

  • Name: Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-
  • Synonyms: Mianserine [INN-French]; Mianserinum [INN-Latin]; Mianserina [INN-Spanish]; Mianseryna [Polish]; Mianserinum;Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-; Mianserina;Mianserine;
  • CAS Registry Number:
  • Transport: 3249
  • Flash Point: 186.1°C
  • Boiling Point: 411.3°Cat760mmHg
  • Density: 1.18g/cm3
  • Safety Statements: Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: agranulocytosis. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 186.1°C
  • EINECS: 246-088-6
  • Molecular Weight: 264.3648
  • InchiKey: UEQUQVLFIPOEMF-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18
    (20)13-19/h2-9,18H,10-13H2,1H3
  • Molecular Formula: C18H20N2
  • Molecular Structure:CAS No:24219-97-4 Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-

Related products

Search by region :

Select to

24219-97-4 Mianserin

  • IUPAC NAME-(±)-2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepin MOLECULAR FORMULA-C18H20N2 MOLAR MASS-264.365 Mianserin is a psychoactive drug of the tetracyclic antidepressant (TeCA) therapeutic family Its efficacy, in the treatmen...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool Aurangabad,MaharashtraIndia
Contact Supplier

24219-97-4 Mianserin

Contact Supplier

24219-97-4 MIANSERIN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
Contact Supplier

24219-97-4 MIANSERIN

  • United States ACIC [Manufacturer]
  • Tel: 800-265-6727/ 519-751-3668
  • Fax: 519-751-1378
  • Address: 11772 West Sample Road,
    Coral Springs, Florida, 33065 USA null,nullUnited States
Contact Supplier

24219-97-4 Mianserin

Contact Supplier

24219-97-4 MIANSERIN (1.0MG/ML METHANOL)

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-
Title: Mianserin
CAS Registry Number: 24219-97-4
CAS Name: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine
Synonyms: 2-methyl-1,2,3,4,10,14b-hexahydro-2H-pyrazino[1,2-f]morphanthridine
Molecular Formula: C18H20N2
Molecular Weight: 264.36
Percent Composition: C 81.78%, H 7.63%, N 10.60%
Literature References: Serotonin receptor antagonist. Prepn: NL 6603256; van der Burg, Delobelle, US 3534041 (1967, 1970, both to Organon); van der Burg et al., J. Med. Chem. 13, 35 (1970). Pharmacology: Saxena et al., Eur. J. Pharmacol. 13, 295 (1971); Vargaftig et al., ibid. 16, 336 (1971); Van Riezen, Arch. Int. Pharmacodyn. Ther. 198, 256 (1972). Molecular and crystal structure: van Rij, Feil, Tetrahedron 29, 1891 (1973). Review of pharmacology and therapeutic efficacy in depressive illness: R. N. Brogden et al., Drugs 16, 273-301 (1978). 5HT-receptor binding study: B. S. Alexander, M. D. Wood, J. Pharm. Pharmacol. 39, 664 (1987). Review: H. van Riezen et al., in Pharmacological and Biochemical Properties of Drug Substances vol. 3, M. E. Goldberg, Ed. (Am. Pharm. Assoc., Washington, DC, 1981) pp 56-93; Br. J. Clin. Pharmacol. 15, Suppl. 2, S141-S342 (1983).
 
Derivative Type: Hydrochloride
CAS Registry Number: 21535-47-7
Manufacturers' Codes: GB-94; Org-GB-94
Trademarks: Athymil (Organon); Bolvidon (Organon); Lantanon (Ravasini); Norval (Bencard); Tetramide (Sankyo); Tolvin (Organon); Tolvon (Organon)
Molecular Formula: C18H20N2.HCl
Molecular Weight: 300.83
Percent Composition: C 71.87%, H 7.04%, N 9.31%, Cl 11.79%
Properties: mp 282-284°. LD50 in male, female mice (mg/kg): 365, 390 orally; 32.5, 31.0 i.v. (van Riezen).
Melting point: mp 282-284°
Toxicity data: LD50 in male, female mice (mg/kg): 365, 390 orally; 32.5, 31.0 i.v. (van Riezen)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tetracyclics.