Title: Firocoxib
CAS Registry Number: 189954-96-9
CAS Name: 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5
H)-furanone
Manufacturers' Codes: ML-1785713
Trademarks: Previcox (Merial)
Molecular Formula: C17H20O5S
Molecular Weight: 336.40
Percent Composition: C 60.70%, H 5.99%, O 23.78%, S 9.53%
Literature References: Selective cyclooxygenase-2 (COX-2) inhibitor. Prepn: M. Belley
et al., WO 9714691;
eidem US 5981576 (1997, 1999 both to Merck Frosst). Pharmacokinetics and therapeutic efficacy in inflammatory synovitis in dogs: M. E. McCann
et al., Am. J. Vet. Res. 65, 503 (2004).
Therap-Cat-Vet: Anti-inflammatory; analgesic.