Home > Name List By 3 > 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4, 3-fg]quinoline-9-yl]-1,1-diethylurea

CAS No 18016-80-3 , 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,
3-fg]quinoline-9-yl]-1,1-diethylurea

  • Name: 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,
    3-fg]quinoline-9-yl]-1,1-diethylurea
  • Synonyms: 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,
    3-fg]quinoline-9-yl]-1,1-diethylurea; Lisuride [INN]; Lisurida [INN-Spanish]; Lysurid; Lisurida; Lisuridum;Lysuride; Lisuridum [INN-Latin]; lisuride maleate;
  • CAS Registry Number:
  • Flash Point: 318.7°C
  • Boiling Point: 603.4°Cat760mmHg
  • Density: 1.23g/cm3
  • Refractive index: 1.659
  • Flash Point: 318.7°C
  • EINECS: 241-925-1
  • Molecular Weight: 338.44664
  • InchiKey: BKRGVLQUQGGVSM-KBXCAEBGSA-N
  • InChI: InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13
    (11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,
    22,25)/t14-,18+/m0/s1
  • Molecular Formula: C20H26N4O
  • Molecular Structure:CAS No:18016-80-3 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,<br />3-fg]quinoline-9-yl]-1,1-diethylurea

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18016-80-3 CABERQOLINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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18016-80-3 LISURIDE

  • United States ChemPacific Corporation [Manufacturer]
  • Tel: 410-633-5771
  • Fax: 410-633-5808
  • Address: 6200 Freeport Center
    Baltimore, MD 21224, USA null,nullUnited States
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References of 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,
3-fg]quinoline-9-yl]-1,1-diethylurea
Title: Lisuride
CAS Registry Number: 18016-80-3
CAS Name: N￠-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethylurea
Synonyms: 9-(3,3-diethylureido)-4,6,6a,7,8,9-hexahydro-7-methylindolo[4,3-f,g]quinoline; 1,1-diethyl-3-(D-6-methylisoergolen-8-yl)urea; N-(D-6-methyl-8-isoergolenyl)-N,N-diethylurea; methylergol carbamide; lysuride
Molecular Formula: C20H26N4O
Molecular Weight: 338.45
Percent Composition: C 70.97%, H 7.74%, N 16.55%, O 4.73%
Literature References: Dopamine D2-receptor agonist. Prepn: V. Zikan, M. Semonsky, Collect. Czech. Chem. Commun. 25, 1922 (1960); eidem, Pharmazie 23, 147 (1968). Pharmacology and toxicity: Z. Votava, I. Lamplova, Physiol. Bohemoslov. 12, 37 (1963), C.A. 59, 9221d (1963).
Properties: Crystals from benzene, mp 186°. [a]D20 +313° (c = 0.60 in pyridine).
Melting point: mp 186°
Optical Rotation: [a]D20 +313° (c = 0.60 in pyridine)
 
Derivative Type: Maleate
CAS Registry Number: 19875-60-6
Trademarks: Apodel (Meiji); Cuvalit (Schering AG); Dopergin (Schering AG); Eunal (Schering); Lysenyl (Spofa); Revanil (Roche)
Molecular Formula: C20H26N4O.C4H4O4
Molecular Weight: 454.52
Percent Composition: C 63.42%, H 6.65%, N 12.33%, O 17.60%
Properties: Prisms from ethanol, mp 200° (dec). [a]D20 +288° (c = 0.5 in methanol). uv max (methanol): 313 nm. LD50 i.v. in mice: 14.4 mg/kg (Votava, Lamplova).
Melting point: mp 200° (dec)
Optical Rotation: [a]D20 +288° (c = 0.5 in methanol)
Absorption maximum: uv max (methanol): 313 nm
Toxicity data: LD50 i.v. in mice: 14.4 mg/kg (Votava, Lamplova)
 
Therap-Cat: Antimigraine; prolactin inhibitor; antiparkinsonian.
Keywords: Antimigraine; Dopamine Receptor Agonist; Prolactin Inhibitor.