Home > Name List By v > Vancomycin,22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-,(...

CAS No 171099-57-3 , Vancomycin,22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-,(4''R)-

  • Name: Vancomycin,22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-,(4''R)-
  • Synonyms: Oritavancin;Vancomycin,22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-,(4''R)-;LY333328;
  • CAS Registry Number:
  • Molecular Weight: 0
  • InChI: InChI=1S/C86H97Cl3N10O26/c1-35(2)22-51(92-7)77(110)98-67-69(105)42-15-20-55(49(88)24-42)120-57-26-44-27-58(73(57)125-84-74(71(107)70(106)59(34-100)122-84)124-62-32-86(6,76(109)37(4)119-62)93-33-38-8-10-39(11-9-38)40-12-17-45(87)18-13-40)121-56-21-16-43(25-50(56)89)72(123-61-31-85(5,91)75(108)36(3)118-61)68-82(115)97-66(83(116)117)48-28-46(101)29-54(103)63(48)47-23-41(14-19-53(47)102)64(79(112)99-68)96-80(113)65(44)95-78(111)52(30-60(90)104)94-81(67)114/h8-21,23-29,35-37,51-52,59,61-62,64-72,74-76,84,92-93,100-103,105-109H,22,30-34,91H2,1-7H3,(H2,90,104)(H,94,114)(H,95,111)(H,96,113)(H,97,115)(H,98,110)(H,99,112)(H,116,117)/t36-,37-,51+,52-,59+,61-,62-,64+,65+,66+,67+,68-,69+,70+,71-,72+,74+,75-,76-,84-,85-,86-/m0/s1
  • Molecular Formula: C86H97 Cl3 N10 O26
  • Molecular Structure:CAS No:171099-57-3 Vancomycin,22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-,(4''R)-

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171099-57-3 ORITAVANCIN

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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References of Vancomycin,22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3''-[(4'-chloro[1,1'-biphenyl]-4-yl)methyl]-,(4''R)-
Title: Oritavancin
CAS Registry Number: 171099-57-3
CAS Name: (4￠￠R)-22-O-(3-Amino-2,3,6-trideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-N3￠￠-[(4￠-chloro[l,1￠-biphenyl]-4-yl)methyl]vancomycin
Manufacturers' Codes: LY-333328
Molecular Formula: C86H97Cl3N10O26
Molecular Weight: 1793.10
Percent Composition: C 57.61%, H 5.45%, Cl 5.93%, N 7.81%, O 23.20%
Literature References: Semisynthetic glycopeptide antibiotic. Prepn: R. D. G. Cooper et al., WO 9630401; eidem US 5840684 (1996, 1998 both to Eli Lilly). In vitro antibacterial activity: F. Biavasco et al., Antimicrob. Agents Chemother. 41, 2165 (1997). Mechanism of action: N. E. Allen, T. I. Nicas, FEMS Microbiol. Rev. 26, 511 (2003). Clinical pharmacokinetics: S. M. Bhavnani et al., Diagn. Microbiol. Infect. Dis. 50, 95 (2004); G. J. Fetterly et al., Antimicrob. Agents Chemother. 49, 148 (2005). Clinical evaluation in Staphylococcus aureus bacteremia: S. M. Bhavnani et al., ibid. 50, 994 (2006). Review of pharmacology and clinical development: D. R. P. Guay, Pharmacotherapy 24, 58-68 (2004).
 
Derivative Type: Diphosphate
CAS Registry Number: 192564-14-0
Molecular Formula: C86H97Cl3N10O26.2H3PO4
Molecular Weight: 1989.09
Percent Composition: C 51.93%, H 5.22%, Cl 5.35%, N 7.04%, O 27.35%, P 3.11%
Properties: Sol in water.
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Polypeptides.