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CAS No 7059-24-7 , D-threo-2-Pentulose,1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-a-D-lyxo-hexopyranosyl)-b-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl-(1®

  • Name: D-threo-2-Pentulose,1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-a-D-lyxo-hexopyranosyl)-b-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl-(1®
  • Synonyms: Antibiotic B 599; NSC 58514; Toyomycin;3)-O-2,6-dideoxy-b-D-arabino-hexopyranosyl-(1®3)-2,6-dideoxy-b-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-,(1S)-;Aburamycin B; Olivomycin D, 3D-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-7-methyl-;ChromomycinA3 (8CI); CMA3;D-threo-2-Pentulose,1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-a-D-lyxo-hexopyranosyl)-b-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl-(1®
  • CAS Registry Number:
  • Transport: UN 3462 6.1/PG 1
  • Flash Point: 311.1°C
  • Boiling Point: 1147.6°C at 760 mmHg
  • Density: 1.43g/cm3
  • Refractive index: 1.608
  • Safety Statements: A deadly poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and fumes.
  • Hazard Symbols: T+,T
  • Flash Point: 311.1°C
  • EINECS: 230-348-0
  • Molecular Weight: 1183.39
  • InChI: InChI=1/C57H82O26/c1-21-34(79-40-19-37(53(26(6)75-40)77-28(8)59)82-38-16-33(61)52(70-11)25(5)74-38)15-31-13-30-14-32(54(71-12)51(68)46(63)22(2)58)55(50(67)44(30)49(66)43(31)45(21)62)83-41-18-35(47(64)24(4)73-41)80-39-17-36(48(65)23(3)72-39)81-42-20-57(10,69)56(27(7)76-42)78-29(9)60/h13,15,22-27,32-33,35-42,46-48,52-56,58,61-66,69H,14,16-20H2,1-12H3/t22-,23-,24-,25-,26-,27+,32+,33-,35-,36-,37-,38-,39+,40+,41+,42+,46+,47-,48-,52+,53+,54+,55+,56+,57+/m1/s1
  • Risk Statements: 61-28
  • Molecular Formula: C57H82 O26
  • Molecular Structure:CAS No:7059-24-7 D-threo-2-Pentulose,1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-a-D-lyxo-hexopyranosyl)-b-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl-(1®
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7059-24-7 CHROMOMYCIN A3

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany ,Germany
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7059-24-7 Chromomycin A3, 99%

  • Chromomycin A3, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,China
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7059-24-7 Chromomycin A3

  • Chromomycin A3
  • Germany IRIS Biotech GmbH [Manufacturer]
  • Tel: +49 9231 9619 73
  • Fax: +49 9231 9619 99
  • Address: IRIS Biotech GmbH
    Waldershofer Str. 49-51
    D-95615 Marktredwitz, Germany ,Germany
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7059-24-7 Chromomycin A3, > 96 %

  • Chromomycin A3, > 96 %
  • United Kingdom Fluorochem Ltd. [Importer/Exporter]
  • Tel: (01457) 868921 (4 lines)
  • Fax: (01457) 869360/860927
  • Address: Wesley Street, Old Glossop, Derbyshire SK13 7RY Old Glossop,DerbyshireUnited Kingdom
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7059-24-7 Chromomycin A3

  • Chromomycin A3
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,United States
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7059-24-7 SC-200907 CHROMOMYCIN A3

  • United States Santa Cruz Biotechnology, Inc. [Manufacturer]
  • Tel: 831-457-3800/ 800-457-3801
  • Fax: 831-457-3801
  • Address: Santa Cruz Biotechnology, Inc.
    2145 Delaware Ave.
    Santa Cruz, CA 95060 ,United States
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7059-24-7 Chromomycin A3

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7059-24-7 Chromomycin A3, > 95% by TLC. > 93% by HPLC

  • Chromomycin A3, > 95% by TLC. > 93% by HPLC
  • Israel Fermentek Ltd [Manufacturer]
  • Tel: 972 2 5853853
  • Fax: 972 2 5853843
  • Address: ,Israel
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7059-24-7 Chromomycin A3

  • Chromomycin A3
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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7059-24-7 Chromomycin A3

  • Chromomycin A3
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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References of D-threo-2-Pentulose,1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-a-D-lyxo-hexopyranosyl)-b-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl-(1®
Title: Chromomycin A3
CAS Registry Number: 7059-24-7
CAS Name: (1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-a-D-lyxo-hexopyranosyl)-b-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl-(1?3)-O-2,6-dideoxy-b-D-arabino-hexopyranosyl-(1?3)-2,6-dideoxy-b-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-D-threo-2-pentulose
Synonyms: 3D-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-a-L-arabino-hexopyranosyl)-7-methylolivomycin D; aburamycin B; toyomycin
Molecular Formula: C57H82O26
Molecular Weight: 1183.25
Percent Composition: C 57.86%, H 6.99%, O 35.16%
Literature References: Major component of an antitumor antibiotic complex produced by Streptomyces griseus. Binds specifically to guanine-cytosine base pairs in DNA; does not intercalate. The aglycone, chromomycinone, is identical to that of plicamycin, q.v. Isoln of complex and antibacterial activity: M. Shibata et al., J. Antibiot. 13B, 1 (1960), C.A. 54, 22835g (1960). Characterization: K. Mizuno, J. Antibiot. 16A, 22 (1963). Structure: M. Miyamoto et al., Tetrahedron 23, 421 (1967). Abs config: N. Harada et al., J. Am. Chem. Soc. 91, 5896 (1969). Revised structure: J. Thiem, B. Meyer, J. Chem. Soc. Perkin Trans. 2 1979, 1331. Pharmacology and toxicity: M. Slavik, S. K. Carter, Adv. Pharmacol. Chemother. 12, 1 (1975). Fluorescence characteristics: R. H. Jensen, J. Histochem. Cytochem. 25, 573 (1977). Use for analysis and identification of chromosomes: J. H. van de Sande et al., Science 195, 400 (1977); in high-speed chromosome sorting: J. W. Gray et al., ibid. 238, 323 (1987); in flow karyotyping: M. F. Bartholdi, Pathobiology 58, 118 (1990). Review of staining methods: H. A. Crissman, R. A. Tobey, Methods Cell Biol. 33, 97-103 (1990).
Properties: Yellow powder, dec. 185°. [a]D23 -57° (ethanol). uv max (ethanol): 230, 281, 304, 318, 330, 412 nm (log e 4.39, 4.72, 3.85, 3.92, 3.84, 4.07). Excitation max: ~445 nm. Emission max: ~575 nm. Sol in ethanol, ethyl acetate, DMSO, methanol. LD50 in mice (mg/kg): 1.85 i.v. (Slavik, Carter). Protect from light.
Optical Rotation: [a]D23 -57° (ethanol)
Absorption maximum: uv max (ethanol): 230, 281, 304, 318, 330, 412 nm (log e 4.39, 4.72, 3.85, 3.92, 3.84, 4.07)
Toxicity data: Excitation max: ~445 nm. Emission max: ~575 nm. Sol in ethanol, ethyl acetate, DMSO, methanol. LD50 in mice (mg/kg): 1.85 i.v. (Slavik, Carter).
Use: Fluorescent DNA stain in flow cytometry and karyotype analysis of chromosomes.