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CAS No 16816-67-4 , D-Pantethine

  • Name: D-Pantethine
  • Synonyms: D-Pantethine;Bis(N-pantothenylamidoethyl) disulfide; (2R)-N-[3-[2-[2-[3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide;
  • CAS Registry Number:
  • Flash Point: 550.8°C
  • Boiling Point: 987.2°Cat760mmHg
  • Density: 1.277g/cm3
  • Safety Statements: Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx. See also AMIDES.
  • Flash Point: 550.8°C
  • EINECS: 240-842-8
  • Molecular Weight: 554.72
  • InChI: InChI=1S/C22H42N4O8S2/c1-21(2,13-27)17(31)19(33)25-7-5-15(29)23-9-11-35-36-12-10-24-16(30)6-8-26-20(34)18(32)22(3,4)14-28/h17-18,27-28,31-32H,5-14H2,1-4H3,(H,23,29)(H,24,30)(H,25,33)(H,26,34)/t17-,18-/m0/s1
  • Molecular Formula: C22H42N4O8S2
  • Molecular Structure:CAS No:16816-67-4 D-Pantethine
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16816-67-4 D -PANTETHINE ANHYDROUS

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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16816-67-4 Butanamide,N,N'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethyl-,(2R,2'R)-

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
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16816-67-4 Butanamide,N,N'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethyl-,(2R,2'R)-

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16816-67-4; 138148-35-3 Pantethine

  • United Kingdom Fine Chem Trading LTD [Manufacturers]
  • Tel: +44-079-7062-7591
  • Fax: +44-087-0705-2950
  • Address: PO Box 292, Greenford, UB6 9ZL, England London,nullUnited Kingdom
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16816-67-4; 138148-35-3 Pantethine

  • United States Scandinavian Formulas, Inc. null
  • Tel: +1-215-4532507
  • Fax: +1-215-2579781
  • Address: 140 E. Church St. Sellersville, PA 18960 null,nullUnited States
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16816-67-4 Butanamide,N,N'-[dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethyl-,(2R,2'R)-

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16816-67-4 (22''R)-N,N''-[DITHIOBIS[2,1-ETHANEDIYLIMINO(3-OXO-3,1-PROPANEDIYL)]]BIS[2,4-DIHYDROXY-3,3-DIMETHYL-BUTANAMIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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16816-67-4 Pantethine

  • United States FabriChem, Inc. [Manufacturer]
  • Tel: 203-372-8811
  • Fax: 203-372-8816
  • Address: FabriChem, Inc.
    2450 Reservoir Avenue
    Trumbull, CT 06611
    USA null,nullUnited States
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16816-67-4; 138148-35-3 Pantethine

  • United States FabriChem, Inc. [Manufacturer]
  • Tel: 203-372-8811
  • Fax: 203-372-8816
  • Address: FabriChem, Inc.
    2450 Reservoir Avenue
    Trumbull, CT 06611
    USA null,nullUnited States
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16816-67-4 PANTETHINE

  • China Enze Chemicals Co.,Ltd [Manufacturer]
  • Tel: +(86)-(571)-8865-5925/ +86-013750849205 (mobile)
  • Fax: +(86)-(571)5627-7156
  • Address: Industry develop area Meicheng Town,
    Jiande, H/Z, China null,nullChina
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References of D-Pantethine
Title: Pantethine
CAS Registry Number: 16816-67-4
CAS Name: N,N¢-[Dithiobis[2,1-ethanediylimino(3-oxo-3,1-propanediyl)]]bis[2,4-dihydroxy-3,3-dimethylbutanamide]
Synonyms: N,N¢-[dithiobis(ethyleneiminocarbonylethylene)]bis(2,4-dihydroxy-3,3-dimethylbutyramide); D-bis(N-pantothenyl-b-aminoethyl) disulfide
Trademarks: Lipodel (Delalande); Pantetina (Maggioni); Panthecin (Sawai); Pantomin (Daiichi); Pantosin (Daiichi)
Molecular Formula: C22H42N4O8S2
Molecular Weight: 554.72
Percent Composition: C 47.63%, H 7.63%, N 10.10%, O 23.07%, S 11.56%
Line Formula: [HOCH2C(CH3)2CHOHCONHCH2CH2CONHCH2CH2S]2
Literature References: Disulfide dimer of pantetheine, q.v. Growth factor for Lactobacillus bulgaricus: Williams et al., J. Biol. Chem. 177, 933 (1949). Formed by oxidation of pantetheine: Brown, Snell, J. Biol. Chem. 198, 375 (1952). Structure: Snell et al., J. Am. Chem. Soc. 72, 5349 (1950). Synthesis: Wieland, Bokelmann, Naturwissenschaften 38, 384 (1951); Wittle et al., J. Am. Chem. Soc. 75, 1694 (1953); Viscontini et al., Helv. Chim. Acta 37, 375 (1954); Bowman, Cavalla, J. Chem. Soc. 1954, 1171; Shimizu et al., Chem. Pharm. Bull. 13, 180 (1965). Clinical trial in hyperlipoproteinemia: A. Gaddi et al., Atherosclerosis 50, 73 (1984).
Properties: Glassy, colorless to light yellow substance. [a]D27 +13.5° (c = 3.75 in water). Freely sol in water; less sol in ethanol. Practically insol in ether, acetone, ethyl acetate, benzene, chloroform.
Optical Rotation: [a]D27 +13.5° (c = 3.75 in water)
Therap-Cat: Antilipemic.
Keywords: Antilipemic.