Home > Name List By 3 > 3-(cyclopropylmethoxy)-N-(3, 5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

CAS No 162401-32-3 , 3-(cyclopropylmethoxy)-N-(3,
5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

  • Name: 3-(cyclopropylmethoxy)-N-(3,
    5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
  • Synonyms: 1xoq;162401-32-3; 1xmu;3-(cyclopropylmethoxy)-N-(3,
    5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide; Daliresp; 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE; DAXAS;
  • CAS Registry Number:
  • Density: 1.466 g/cm3
  • Refractive index: 1.603
  • Molecular Weight: 403.207466
  • InchiKey: MNDBXUUTURYVHR-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13
    (26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
  • Molecular Formula: C17H14Cl2F2N2O3
  • Molecular Structure:CAS No:162401-32-3 3-(cyclopropylmethoxy)-N-(3,<br />5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

Related products

Search by region :

Select to

162401-32-3 Roflumilast

Contact Supplier

162401-32-3 Roflumilast

  • Roflumilast
  • India J.INC. [Manufacturer]
  • Tel: +91 79 30071152, 30071190, 30071175, 30071153
  • Fax: +91 79 30071176, 26574630
  • Address: # 95, Rangwala Towers, Law garden, Ellisbridge, Ahmedabad 380006, Gujarat State, India. 380006 AhmedabadINDIA Ahmedabad,nullIndia
Contact Supplier

162401-32-3 ROFLUMILAST

  • United States GLSynthesis Inc. [Manufacturer]
  • Tel: 508 754-6700
  • Fax: 508 754-7075
  • Address: GLSynthesis Inc.
    One Innovation Drive
    Worcester MA 01605 null,nullUnited States
Contact Supplier

162401-32-3 Roflumilast

  • China Luna Chemicals Co.,Ltd. null
  • Fax: +86-571-85775960
  • Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China null,nullChina
Contact Supplier

162401-32-3 Benzamide,3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-

Contact Supplier

162401-32-3 Roflumilast

  • India Exim-Pharm International null
  • Tel: +91-(22)-26191948
  • Fax: +91-(22)-26191948
  • Address: 1, Ashish Mahal, 2nd Floor, Ist Road, Golibar Santacruz (E), Mumbai, Maharashtra 400 055, null,nullIndia
Contact Supplier

162401-32-3 ROFLUMILAST

  • China Rota Pharm and Chem Co., Ltd. null
  • Fax: +86-571-87918114
  • Address: Room 401,Hangzhou Friendship Plaza,No.74 Bbaochu Road, Hangzhou, China null,nullChina
Contact Supplier

162401-32-3 Benzamide,3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-

  • China Rota Pharm & Chem Co., Ltd. null
  • Tel: +86-(571)-8836-9502
  • Fax: +86-(571)-8791-8114
  • Address: Room 401,Hangzhou Friendship Plaza,No.74 Bbaochu Road, Hangzhou, Zhejiang, null,nullChina
Contact Supplier

162401-32-3 Benzamide,3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-

  • India Manus Aktteva, India [Manufacturers]
  • Tel: +91 79 30071152
  • Fax: +919879167919
  • Address: India - Gujarat Gujarat,GujaratIndia
Contact Supplier

162401-32-3 Benzamide,3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-

Contact Supplier

Select to

3/4
Previous 1 2 3 4 Next
References of 3-(cyclopropylmethoxy)-N-(3,
5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Title: Roflumilast
CAS Registry Number: 162401-32-3
CAS Name: 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
Manufacturers' Codes: BY-217
Trademarks: Daxas (Altana)
Molecular Formula: C17H14Cl2F2N2O3
Molecular Weight: 403.21
Percent Composition: C 50.64%, H 3.50%, Cl 17.59%, F 9.42%, N 6.95%, O 11.90%
Literature References: Selective phosphodiesterase 4 (PDE4) inhibitor. Prepn: D. Flockerzi et al., WO 9501338; H. Amschler, US 5712298 (1995, 1998 both to Byk-Gulden). Pharmacology: A. Hatzelmann, C. Schudt, J. Pharmacol. Exp. Ther. 297, 267 (2001); D. S. Bundschuh et al., ibid. 280. Clinical evaluation in allergic rhinitis: B. M. W. Schmidt et al., J. Allergy Clin. Immunol. 108, 530 (2001); in exercise-induced asthma: W. Timmer et al., J. Clin. Pharmacol. 42, 297 (2002); in COPD: K. F. Rabe et al., Lancet 366, 563 (2005). Comparative review with cilomilast: M. A. Giembycz, Monaldi Arch. Chest Dis. 57, 48-64 (2002).
Properties: Crystals from isopropanol, mp 158°.
Melting point: mp 158°
Therap-Cat: Antiasthmatic; in treatment of chronic obstructive pulmonary disease.
Keywords: Antiasthmatic (Nonbronchodilator); Phosphodiesterase Inhibitor.