Home > Name List By 2 > 2-[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11, 12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5, 5a-tetrahydrotetracene-2-c...

CAS No 15599-51-6 , 2-[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,
12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,
5a-tetrahydrotetracene-2-carbonyl]amino]-2-[4-(2-hydroxyethyl)piperazin-
1-yl]acetic acid

  • Name: 2-[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,
    12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,
    5a-tetrahydrotetracene-2-carbonyl]amino]-2-[4-(2-hydroxyethyl)piperazin-
    1-yl]acetic acid
  • Synonyms: Apicyclinum;Apicyclina; UNII-T1Y573BS7H; Apicycline [INN]; 15599-51-6; AC1NURO5;2-[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,
    12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,
    5a-tetrahydrotetracene-2-carbonyl]amino]-2-[4-(2-hydroxyethyl)piperazin-
    1-yl]acetic acid; SureCN1479627; Apicyclin; RIT 1140;
  • CAS Registry Number:
  • Flash Point: 483.7°C
  • Boiling Point: 876.2°Cat760mmHg
  • Density: 1.62g/cm3
  • Refractive index: 1.73
  • Flash Point: 483.7°C
  • Molecular Weight: 630.64292
  • InchiKey: FFWUFMNATRIODI-GMJIGYHYSA-N
  • InChI: InChI=1S/C30H38N4O11/c1-29(44)14-5-4-6-17(36)18(14)22(37)19-15(29)13-16-
    21(32(2)3)23(38)20(25(40)30(16,
    45)24(19)39)27(41)31-26(28(42)43)34-9-7-33(8-10-34)11-12-35/h4-6,15-16,
    21,26,35-37,40,44-45H,7-13H2,1-3H3,(H,31,41)(H,42,43)/t15-,16-,21-,26?,
    29+,30-/m0/s1
  • Molecular Formula: C30H38N4O11
  • Molecular Structure:CAS No:15599-51-6 2-[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,<br />12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,<br />5a-tetrahydrotetracene-2-carbonyl]amino]-2-[4-(2-hydroxyethyl)piperazin-<br />1-yl]acetic acid

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15599-51-6 Apicycline

  • Apicycline, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
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15599-51-6 Apicycline

  • Apicycline, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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References of 2-[[(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,
12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,
5a-tetrahydrotetracene-2-carbonyl]amino]-2-[4-(2-hydroxyethyl)piperazin-
1-yl]acetic acid
Title: Apicycline
CAS Registry Number: 15599-51-6
CAS Name: a-[4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido]-4-(2-hydroxyethyl)-1-piperazineacetic acid
Synonyms: N-[(2-hydroxyethyl)piperazinocarboxymethyl]tetracycline
Manufacturers' Codes: RIT-1140
Molecular Formula: C30H38N4O11
Molecular Weight: 630.64
Percent Composition: C 57.14%, H 6.07%, N 8.88%, O 27.91%
Literature References: Semi-synthetic antibiotic similar to tetracycline. Prepn: Rondelet, NL 6515688 C.A. 66, 46260a (1967) and BE 673130 C.A. 68, 104840u (1968) (both 1966 to Recherche & Ind. Ther.); Valcavi et al., Farmaco Ed. Sci. 21, 775 (1966); Rondelet, Froment, Ann. Pharm. Fr. 26, 63 (1968).
Properties: Yellow, amorphous powder with slight amine odor, mp 144.5° (dec). Freely sol in water. [a]D -123° (c = 0.5 in methanol); [a]D -133° (c = 0.5 in water).
Melting point: mp 144.5° (dec)
Optical Rotation: [a]D -123° (c = 0.5 in methanol); [a]D -133° (c = 0.5 in water)
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); Tetracyclines.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.