Home > Name List By 1 > 1,3-bis(2-chloroethyl)-1-nitrosourea

CAS No 154-93-8 , 1,3-bis(2-chloroethyl)-1-nitrosourea

  • Name: 1,3-bis(2-chloroethyl)-1-nitrosourea
  • Synonyms: Bi CNU; Carmubris;BCNU;1,3-bis(2-chloroethyl)-1-nitrosourea; 1,3-Bis(2-chloroethyl)-1-nitrosourea; BiCNU; 154-93-8; Gliadel; Carmustin; Nitrumon;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 30 ºC
  • Boiling Point: 404
  • Density: 1.46 g/ml
  • Refractive index: 1.548
  • Water Solubility: <0.1 G/100 ML AT 18 ºC
  • Safety Statements: R45;R46;R60;R61;R28
  • Hazard Symbols: T+: Very toxic;
  • EINECS: 205-838-2
  • Molecular Weight: 214.04986
  • InchiKey: DLGOEMSEDOSKAD-UHFFFAOYSA-N
  • InChI: InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
  • Risk Statements: S53;S22;S36/37/39;S45
  • Molecular Formula: C5H9Cl2N3O2
  • Molecular Structure:CAS No:154-93-8 1,3-bis(2-chloroethyl)-1-nitrosourea
Search by region :

Select to

154-93-8 carmustine

  • China Hangzhou Starshine Pharmaceutical Co., LTD [Manufacturers]
  • Tel: +86-571-89939756 85122191
  • Fax: +86-571-85122157
  • Address: ROOM A, 20 TH FLOOR, WEST BUILDING, INTERNATIONAL GARDEN, NO.160 TIANMUSHAN ROAD, HANGZHOU, CHINA null,ZhejiangChina
Contact Supplier

154-93-8 1,3-BIS(2-CHLOROETHYL)NITROSOUREA

Contact Supplier

154-93-8 Carmustine

  • Carmustine
  • Germany Intatrade Chemicals null
  • Tel: ++49-3493-605464
  • Address: Vierzoner Strasse 14 D-06749 Bitterfeld, Germany null,nullGermany
Contact Supplier

154-93-8 Carmustine

  • China Qingdao Chinaoil Co., Ltd null
  • Fax: +86-532-85713888 85723888
  • Address: 22/F,Golden Light Tower,No.56, Xianggang Zhong Road, Qingdao 266071, China null,nullChina
Contact Supplier

154-93-8 Carmustine

  • Carmustine
  • Germany SYNCHEM Laborgemeinschaft OHG [Manufacturer]
  • Tel: +49 (0) 5662 40873-0
  • Fax: +49 (0) 5662 40873-20
  • Address: SYNCHEM Laborgemeinschaft OHG
    Dr. Jaeger & Dr. Drinkuth
    Am Kies 2
    D-34587 Felsberg / Altenburg, Germany null,nullGermany
Contact Supplier

154-93-8 1,3-BIS(2-CHLOROETHYL)NITROSOUREA

  • United States Sciencelab.com, Inc. [Manufacturer]
  • Tel: 281.441.4400/ 800.901.7247
  • Fax: 281.441.4409
  • Address: Sciencelab.com, Inc.
    14025 Smith Rd.
    Houston, TX 77396 null,nullUnited States
Contact Supplier

154-93-8 Carmustine

  • China Facus Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-6237-8411
  • Fax: +86-(574)-6237-8410
  • Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800, Ningbo,ZhejiangChina
Contact Supplier

154-93-8 Carmustine

  • China Huei-Ho International Co., Ltd. [Importer/Exporter]
  • Tel: +86-(21)-6273-7219, 6273-6279
  • Fax: +86-(21)-6129-4387, 62735948
  • Address: 20B,No.2,Lane 600,Peakway Tower,Tianshan Road, Shanghai, shanghai 200051, null,ShanghaiChina
Contact Supplier

154-93-8 Carmustine

  • Carmustine
  • United States LKT Laboratories, Inc [Manufacturer]
  • Tel: (888)-558-5227
  • Fax:
  • Address: 2233 University Ave. West 55114-1600 St. PaulUNITED STATES 55114-1600 St. Paul,nullUnited States
Contact Supplier

154-93-8 Carmustine

  • China Taizhou Crene Chempharm Co., Ltd. null
  • Tel: +86-(576)-88813233
  • Fax: +86-(576)-88670057
  • Address: Weiwu Load Economic Developed Zone, Taizhou, Zhejiang 318000, null,nullChina
Contact Supplier

Select to

References of 1,3-bis(2-chloroethyl)-1-nitrosourea
Title: Carmustine
CAS Registry Number: 154-93-8
CAS Name: N,N¢-Bis(2-chloroethyl)-N-nitrosourea
Synonyms: BCNU
Manufacturers' Codes: NSC-409962
Trademarks: Becenun (BMS); Bicnu (BMS); Carmubris (BMS)
Molecular Formula: C5H9Cl2N3O2
Molecular Weight: 214.05
Percent Composition: C 28.06%, H 4.24%, Cl 33.13%, N 19.63%, O 14.95%
Literature References: Chloroethylnitrosourea derivative with antitumor activity. Similar to chlorozotocin, lomustine, nimustine, ranimustine, q.q.v. Synthesis: Johnston et al., J. Med. Chem. 6, 669 (1963). Properties: Loo et al., J. Pharm. Sci. 55, 492 (1966). Decompn studies as related to antileukemic activity: Montgomery et al., J. Med. Chem. 10, 668 (1967). Antifungal action: Hunt, Pittilo, Antimicrob. Agents Chemother. 1965, 710. Toxicology studies: Thompson, Larson, Toxicol. Appl. Pharmacol. 21, 405 (1972). Review of pulmonary toxicity: A. C. Smith, Pharmacol. Ther. 41, 443-460 (1989).
Properties: Light yellow powder that melts to an oily liquid; mp 30-32°. Both powder and liquid are stable. Dec rapidly in acid and in soln above pH 7. Most stable in petroleum ether or aqueous soln at pH 4. Non-ionized at pH 7 with consequent high lipid solubility. Sol in water up to 4 mg/ml and in 50% ethanol up to 150 mg/ml: DeVita et al., Cancer Res. 25, 1876 (1965). LD50 in mice (mg/kg): 19-25 orally, 26 i.p., 24 s.c.; in rats (mg/kg): 30-34 orally (Thompson, Larson).
Melting point: mp 30-32°
Toxicity data: LD50 in mice (mg/kg): 19-25 orally, 26 i.p., 24 s.c.; in rats (mg/kg): 30-34 orally (Thompson, Larson)
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-53.
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents; Nitrosoureas.