CAS No 152-02-3 , Morphinan-3-ol,17-(2-propen-1-yl)-

Name: Morphinan-3-ol,17-(2-propen-1-yl)-
Synonyms: Levallorphanum [INN-Latin]; Levalorfano [INN-Spanish]; Levallofano [DCIT];Morphinan-3-ol,17-(2-propen-1-yl)-; Levallorphane [INN-French]; Lorfan;Naloxiphan;
CAS Registry Number:152-02-3
Flash Point: 214.2°C
Boiling Point: 433.5°Cat760mmHg
Density: 1.14g/cm³
Refractive index: 1.614
Safety Statements: Poison experimentally by subcutaneous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also ALLYL COMPOUNDS.
Flash Point: 214.2°C
EINECS: 205-799-1
Molecular Weight: 283.4079
InchiKey: OZYUPQUCAUTOBP-QXAKKESOSA-N
InChI: InChI=1S/C19H25NO/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15
(21)13-17(14)19/h2,6-7,13,16,18,21H,1,3-5,8-12H2/t16-,18+,19+/m0/s1
Molecular Formula: C₁₉H₂₅NO
Molecular Structure:

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References of Morphinan-3-ol,17-(2-propen-1-yl)-

Title: Levallorphan
CAS Registry Number: 152-02-3
CAS Name: 17-(2-Propenyl)morphinan-3-ol
Synonyms: l,N-allyl-3-hydroxymorphinan; l-3-hydroxy-N-allylmorphinan
Molecular Formula: C19H25NO
Molecular Weight: 283.41
Percent Composition: C 80.52%, H 8.89%, N 4.94%, O 5.65%
Literature References: Prepn from 3-hydroxy-N-methylmorphinan: Schnider, Grüssner, Helv. Chim. Acta 34, 2211 (1951). Alternate route: Hellerbach et al., ibid. 39, 429 (1956). Comprehensive description: B. C. Rudy, B. Z. Senkowski, Anal. Profiles Drug Subs. 2, 339-361 (1973).
Properties: Crystals from dilute ethanol, mp 180-182°. [a]D20 -88.9° (c = 3 in methanol).
Melting point: mp 180-182°
Optical Rotation: [a]D20 -88.9° (c = 3 in methanol)

Derivative Type: Tartrate
CAS Registry Number: 71-82-9
Trademarks: Lorfan (Roche)
Molecular Formula: C19H25NO.C4H6O6
Molecular Weight: 433.49
Percent Composition: C 63.73%, H 7.21%, N 3.23%, O 25.84%
Properties: Crystals from ethanol, mp 176-177°. [a]D16 -39°. Soluble in water.
Melting point: mp 176-177°
Optical Rotation: [a]D16 -39°

Therap-Cat: Narcotic antagonist.
Therap-Cat-Vet: Narcotic antagonist.
Keywords: Narcotic Antagonist.