Home > Name List By 1 > 1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4- methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione

CAS No 149908-53-2 , 1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-
methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione

  • Name: 1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-
    methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione
  • Synonyms: CHEBI:308679; LS-187295; 149908-53-2;1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-
    methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione; UNII-74QU6P2934;Azimilide [INN:BAN]; CHEMBL123558; C23H28ClN5O3; LS-173360; AC1Q3T08;
  • CAS Registry Number:
  • Density: 1.32 g/cm3
  • Molecular Weight: 457.95312
  • InchiKey: MREBEPTUUMTTIA-PCLIKHOPSA-N
  • InChI: InChI=1S/C23H28ClN5O3/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29
    (23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18/h4-9,16H,2-3,10-15,
    17H2,1H3/b25-16+
  • Molecular Formula: C23H28ClN5O3
  • Molecular Structure:CAS No:149908-53-2 1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-<br />methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione

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References of 1-[(E)-[5-(4-chlorophenyl)furan-2-yl]methylideneamino]-3-[4-(4-
methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione
Title: Azimilide
CAS Registry Number: 149908-53-2
CAS Name: 1-[[[5-(4-Chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione
Molecular Formula: C23H28ClN5O3
Molecular Weight: 457.95
Percent Composition: C 60.32%, H 6.16%, Cl 7.74%, N 15.29%, O 10.48%
Literature References: Potassium channel blocker. Prepn: S. S. Pelosi et al., WO 9304061 (1993 to Procter & Gamble); C.-N. Yu et al., US 5462940 (1995 to Norwich Eaton). Clinical pharmacokinetics: A. Corey et al., J. Clin. Pharmacol. 37, 946 (1997). Clinical trial to improve post-infarct survival: A. J. Camm et al., Am. J. Cardiol. 81, Suppl. 6A, 35D (1998). Review of electrophysiologic properties and pharmacology: R. Karam et al., ibid. 40D-46D.
 
Derivative Type: Dihydrochloride
CAS Registry Number: 149888-94-8
Manufacturers' Codes: NE-10064
Trademarks: Stedicor (Procter & Gamble)
Molecular Formula: C23H28ClN5O3.2HCl
Molecular Weight: 530.88
Percent Composition: C 52.04%, H 5.70%, Cl 20.03%, N 13.19%, O 9.04%
Properties: Crystals from ethanol/water.
 
Therap-Cat: Antiarrhythmic (class III).
Keywords: Antiarrhythmic; Potassium Channel Blocker.