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CAS No 13523-86-9 , 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol

  • Name: 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
  • Synonyms: Carvisken;Visken;1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol; Calvisken; Prinodolol; Durapindol; Pectobloc; Pinbetol; Decreten; Betapindol;
  • CAS Registry Number:
  • Transport: 3249
  • Melting Point: 167-171 ºC
  • Flash Point: 230.3°C
  • Boiling Point: 457.1°Cat760mmHg
  • Density: 1.152g/cm3
  • Safety Statements: R22;R36/37/38
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 230.3°C
  • EINECS: 236-867-9
  • Molecular Weight: 248.3208
  • InchiKey: JZQKKSLKJUAGIC-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/
    h3-7,10-11,15-17H,8-9H2,1-2H3
  • Risk Statements: S26;S36
  • Molecular Formula: C14H20N2O2
  • Molecular Structure:CAS No:13523-86-9 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol

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References of 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
Title: Pindolol
CAS Registry Number: 13523-86-9
CAS Name: 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
Synonyms: 4-[2-hydroxy-3-(isopropylamino)propoxy]indole; prinodolol
Manufacturers' Codes: LB-46
Trademarks: Betapindol (Helvepharm); Blocklin L (Shionogi); Decreten (Dumex); Pectobloc (Kytta-Siegfried); Pinbetol (Dolorgiet); Pindoptan (Kanoldt); Visken (Novartis)
Molecular Formula: C14H20N2O2
Molecular Weight: 248.32
Percent Composition: C 67.71%, H 8.12%, N 11.28%, O 12.89%
Literature References: Mixed b-adrenergic blocker and serotonin 5HT1A-receptor antagonist. Prepn: NL 6601040; F. Troxler, A. Hofmann, US 3471515 (1966, 1969 both to Sandoz). HPLC determn in plasma: H. Smith, J. Chromatogr. 415, 95 (1987). Symposia on cardiovascular pharmacology and clinical studies: Am. Heart J. 104, Suppl. 2, pt. 2, 333-520 (1982); Br. J. Clin. Pharmacol. 13, Suppl. 2, 143S-450S (1982). Effect on serotonin levels in rat brain: L. J. Dreshfield et al., Neurochem. Res. 21, 557 (1996). Clinical trial with fluoxetine, q.v., in depression: V. Pérez et al., Lancet 349, 1594 (1997).
Properties: Crystals from ethanol, mp 171-173°.
Melting point: mp 171-173°
Therap-Cat: Antihypertensive; antianginal; antiarrhythmic; antiglaucoma.
Keywords: ?Adrenergic Blocker; Antianginal; Antiarrhythmic; Antiglaucoma; Antihypertensive; Aryloxypropanolamine Derivatives.