CAS No 131-03-3 , Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a,20a)-

Name: Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a,20a)-
Synonyms: Rauwolscine (6CI,7CI); Isoyohimbine; Corynanthidine; Mesoyohimbine; Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylicacid deriv.; meso-Yohimbine;Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a,20a)-;20a-Yohimban-16b-carboxylic acid, 17a-hydroxy-, methyl ester (8CI); a-Yohimbine;
CAS Registry Number:131-03-3
Transport: 1544
Flash Point: 282.2°C
Boiling Point: 543°Cat760mmHg
Density: 1.31g/cm³
Safety Statements: RIDADR 1544HazardClass 6.1(a)PackingGroup II
Flash Point: 282.2°C
EINECS: 205-006-9
Molecular Weight: 354.44274
InChI: InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1
Molecular Formula: C21H26 N2 O3
Molecular Structure:

Related products

Select to

          
           131-03-3 A-YOHIMBINE
           
             Nanjing Chemlin Chemical Industry Co.,Ltd.
             
              [Manufacturer]
Tel:  +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax:  +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

           131-03-3 Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a,20a)-
           
             BioBioPha Co., Ltd.
             
              [Manufacturer]
Tel: +86-871-5217109
Fax: +86-871-5217109
Address: 132 Lanhei Road, Kunming Institute of Botany, Chinese Academy of Sciences null,nullChina

           131-03-3; 6211-32-1   Alpha Yohimbine
           
             Shanghai Richem International Co., Ltd
             
              null
Tel: +86-21-31263688
Fax: +86-21-51862199
Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road,Pudong, Shanghai (200135), P.R.China null,ShanghaiChina

Select to

1/1

References of Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, (16b,17a,20a)-

Title: a-Yohimbine
CAS Registry Number: 131-03-3
CAS Name: 17a-Hydroxy-20a-yohimban-16b-carboxylic acid methyl ester
Synonyms: corynanthidine; isoyohimbine; mesoyohimbine; rauwolscine
Molecular Formula: C21H26N2O3
Molecular Weight: 354.44
Percent Composition: C 71.16%, H 7.39%, N 7.90%, O 13.54%
Literature References: From bark of Corynanthe johimbe K. Schum., Rubiaceae: Hahn, Brandenburg, Ber. 60, 669 (1927); Wilbaut, van Gastel, Rec. Trav. Chim. 54, 88 (1935); from Rauwolfia canescens L., Apocynaceae: Mookerjee, J. Indian Chem. Soc. 18, 33 (1941), C.A. 35, 7967 (1941); Stoll et al., Helv. Chim. Acta 38, 270 (1955). Identity with corynanthidine: Janot, Goutarel, Bull. Soc. Chim. Fr. 1946, 535. Identity with isoyohimbine: Heinemann, Ber. 60, 15 (1934). Identity with rauwolscine: Chatterjee et al., Chem. Ind. (London) 1954, 491. Structure and stereochemistry: Le Hir et al., Bull. Soc. Chim. Fr. 1953, 1027; Wenkert, Liu, Experientia 11, 302 (1955); Aldrich et al., J. Am. Chem. Soc. 81, 2481 (1959); Janot et al., Bull. Soc. Chim. Fr. 1961, 637. Total synthesis: T?ke et al., J. Org. Chem. 38, 2496 (1973).
Properties: Crystals, mp 243-244°. [a]D19 -18° (pyridine); [a]D19 -27° (abs alcohol). pKa 6.34. uv max (methanol): 227, 281 nm (log e 4.50, 3.93). Sol in warm methanol, ethanol; slightly sol in ether, benzene; practically insol in petr ether, water.
Melting point: mp 243-244°
pKa: pKa 6.34
Optical Rotation: [a]D19 -18° (pyridine); [a]D19 -27° (abs alcohol)
Absorption maximum: uv max (methanol): 227, 281 nm (log e 4.50, 3.93)

Derivative Type: Hydrochloride
Molecular Formula: C21H26N2O3.HCl
Molecular Weight: 390.90
Percent Composition: C 64.52%, H 6.96%, N 7.17%, O 12.28%, Cl 9.07%
Properties: Crystals, mp 288°. [a]D20 +55.5° (water).
Melting point: mp 288°
Optical Rotation: [a]D20 +55.5° (water)